Prize Reinforcement Contingency Management for Cocaine Dependence: a 24-week Randomized Controlled Trial

The purpose of this study is to determine whether prize-based contingency management (prizeCM) combined with cognitive behavioral therapy (CBT) is more effective in the treatment of of cocaine-dependent patients compared to CBT only. Patients were randomized to prizeCM + CBT (experimental group) or to CBT (control group) an treated over 24 weeks. It is the first trial of this type in Europe.

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Key information

Conditions

Cocaine-Related Disorders Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universitäre Psychiatrischen Kliniken, Basel, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

cocaine dependence, aged 18 or older, other dependences

Exclusion criteria

severe somatic, brain, or psychiatric disease, attention deficit disorders with medication methylphenidate

Treatment and study plan

Cognitive Behavioral Therapy (CBT)

Behavioral

Primary outcomes

retention in treatment, cocaine abstinence

Time frame: 24 weeks

cocaine abstinence: at least 3 consecutive weeks of cocaine abstinence, the maximum number of weeks of continous abstinence and proportions of cocaine-free urine samples during the entire 24-week and at 6-month follow-up.

Secondary outcomes

patients' satisfaction with the therapy, clinical measures

Time frame: 24 weeks

patients' satisfaction with prize-based contingency management and with CBT

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Registry information

Important dates

Study start: 2008
Primary completion: 2013
Study completion: 2014
First posted: Apr 7, 2009
Registry last updated: Jan 29, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed