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NCT Number: NCT07177521

Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites

The placement of short implants in post-extraction sockets is a valuable option when residual bone height is limited, minimizing morbidity and treatment time. The management of the peri-implant gap and soft tissues may influence primary stability, hard/soft tissue remodeling, and implant success.

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Key information

Conditions

Edentulous Jaw Jaw Diseases Jaw, Edentulous Mouth Diseases Mouth, Edentulous Musculoskeletal Diseases Periodontal Diseases Stomatognathic Diseases Tooth Diseases Tooth Loss Toothless Mouth

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥18 years.
  • Single-tooth post-extraction sites requiring immediate implant placement in posterior regions (premolars/molars) or selected anterior sites.
  • Planned short implant (≤7-8 mm length, 3.5-5.0 mm diameter).
  • Adequate oral hygiene, no active periodontal disease.
  • Written informed consent.

Exclusion criteria

  • Heavy smoking (>20 cigarettes/day).
  • Uncontrolled diabetes or systemic conditions affecting bone healing.
  • Current bisphosphonate/antiresorptive therapy.
  • Immunosuppression, pregnancy.
  • Poor oral hygiene or acute infection at site.
  • Severe bone dehiscence preventing primary stability.

Treatment and study plan

Insertion of implants in post-extraction tooth

Procedure

Two widely used approaches include:

  • Socket grafting with a fully resorbable synthetic biomaterial (β-tricalcium phosphate + calcium sulfate).
  • Socket grafting with a xenograft and a custom Sealing Socket Abutment (SSA) with a concave emergence profile.

No randomized controlled trials have yet compared these protocols with integrated outcomes including resonance frequency analysis, peri-implant health indices, radiographic bone level changes, and digital intraoral scanning (IOS)-based morphometric analysis.

Primary outcomes

  1. Primary stability

    Time frame: 1 month

    To compare the primary stability (ISQ values at implant insertion) of short implants placed in post-extraction sockets using the two grafting protocols.

Secondary outcomes

  1. Clinical Indices

    Time frame: 12 months

    To assess peri-implant health indices (PD)

  2. Clinical Indices

    Time frame: 12 month

    To assess peri-implant health indices (BoP)

Study contacts

Contact information is provided by the study sponsor or research team.

Giuseppe D'Albis, Dr

CONTACT

[email protected]

+393495103642

Saverio Capodiferro

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

University of Bari Aldo Moro

Other

Registry information

Official study title

Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites: a Randomized Controlled Trial.

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Sep 17, 2025
Registry last updated
Jan 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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