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Completed

NCT Number: NCT02060045

Prevention Ventilator Associated Pneumonia

The objective of the investigators work was to evaluate the impact of 4 sequentially implemented measures for preventing VAP in a major heart surgery ICU. The measures were a specific training program, aspiration of subglottic secretions (ASS), introduction of an inclinometer to improve the semirecumbent position, and reinforcement of oral care with chlorhexidine.

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Key information

Conditions

Ventilator-associated Pneumonia Cross Infection Disease Attributes Healthcare-Associated Pneumonia Iatrogenic Disease Infections Lung Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Pneumonia Pneumonia, Ventilator-Associated Respiratory Tract Diseases Respiratory Tract Infections

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hopsital General Universitario Gregorio Marañon

Madrid, 28007, Spain

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • all patients with heart surgery admitted in critical care unit during the study period

Exclusion criteria

  • none

Treatment and study plan

Bundle implementation

Other

Primary outcomes

  1. Change (reduction) in the incidence density of Ventilator associated pneumonia (VAP)

    Time frame: Baseline and up to 35 months

    Change (reduction) in the incidence density of VAP

Secondary outcomes

  1. Change(length) in Intensive Care Unit (ICU) stay

    Time frame: Baseline and up to 35 months

  2. Change (number of days) in Mechanical Ventilator (MV) per ICU stay

    Time frame: Baseline and up to 35 months

  3. Change in mortality rate

    Time frame: Baseline and up to 35 months

  4. Change in cost of antimicrobial acquisition during ICU stay

    Time frame: Baseline and up to 35 months

  5. Change in compliance with the measures

    Time frame: Baseline and up to 35 months

Sponsors and collaborators

Lead sponsor

Maria Jesus Perez

Other

Collaborators

  • Ciber de Enfermedades Respiratorias
  • Fondo de Investigacion Sanitaria
  • Fundación Rafael del Pino

Registry information

Official study title

Impact of 4 Sequential Measures on the Prevention of Ventilator Associated Pneumonia in Major Heart Surgery Intensive Care Unit

Acronym: REINA

Important dates

Study start
2009
Primary completion
2012
Study completion
2012
First posted
Feb 11, 2014
Registry last updated
Feb 11, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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