Prevention Post Operative Nausea Vomiting in Ambulatory Gynecologic Laparoscopy

The purpose of this study is to compare the incidence of Postoperative nausea and vomiting between the intervention group who received multimodal antiemetic management and the control group who did not get this protocol.

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Key information

Conditions

Postoperative Nausea and Vomiting Nausea Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms Signs and Symptoms, Digestive Vomiting

Age range

18 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 2

Primary location

Anesthesiology Department, Faculty of Medicine, Prince of Songkla University

Hat Yai, Changwat Songkhla, 90110, Thailand

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Ambulatory gynecologic laparoscopy
Age 18-45 years
ASA class 1-2

Exclusion criteria

The patients who take opioid, steroid, pyschotics or antiemetic drug within 24 hours before surgery
History of antiemetic, anesthetic and analgesic drugs allergy
Pregnancy or breast feeding
Body mass index >34 kg/square metre

Treatment and study plan

Dexamethasone

Drug

4 mg iv before induction for high and extremely high risk

Other names: Multimodal antiemetic group :, high risk : dexamethasone 4 mg + ondansetron 4 mg, Extremely high risk : dexamethasone 4 mg +, ondansetron 4 mg +, dimenhydrinate 1 mg

ondansetron

Drug

4 mg iv before ended surgery 30 min

Dimenhydrinate

Drug

1 mg/kg iv before ended surgery 30 min

Primary outcomes

Incidence of PONV in ambulatory gynecologic laparoscopy

Time frame: four year

Sponsors and collaborators

Lead sponsor

Prince of Songkla University

Other

Registry information

Important dates

Study start: 2008
Primary completion: 2011
First posted: Mar 5, 2012
Registry last updated: Jul 31, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed