Prevalence of Thyroid Disorders in Patients With Immune Thrombocytopenic Purpura and Its Impact on Treatment

Prevalence of thyroid disorders in patients with immune thrombocytopenic purpura and its impact on treatment

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Trial opening soon.

Key information

Conditions

Immune Thrombocytopenic Purpura Autoimmune Diseases Blood Coagulation Disorders Blood Platelet Disorders Cytopenia Endocrine System Diseases Hematologic Diseases Hemic and Lymphatic Diseases Hemorrhage Hemorrhagic Disorders Immune System Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Purpura Purpura, Thrombocytopenic Purpura, Thrombocytopenic, Idiopathic Signs and Symptoms Skin Manifestations Thrombocytopenia Thrombotic Microangiopathies Thyroid Diseases Thyroid Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

We investigate patients with ITP for screening of thyroid disorders and how to deal with it and effect of this on the ttt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

ITP patients will be classified as newly diagnosed, persistent and chronic based on duration less than 3 months, 3-12 months, and more than 12 months respectively.

refractory ITP patients.

Exclusion criteria

patients with history of thyroidectomy

patients with history of drug induced ITP
patients with history of HCV, HBV and HIV infection.
Patients who refuse to contribute in this study.

Treatment and study plan

Search for thyroid disorders

Diagnostic Test

TSH , FT3 , FT4

Other names: Laboratory test

Laboratory test

Diagnostic Test

Search for anti thyroid antibodies

Steroid and eltrombopage

Drug

See when we treat thyroid disorders, will patient respond to steroid or eltrombopage?

Other names: Drugs used in ITP

Primary outcomes

Assess the frequency of thyroid disorders in patients with IT

Time frame: Assess the frequency of thyroid disorders in patients with IT

Screening of thyroid disorders in patients with ITP
Evaluate the treatment of thyroid disorders in improvement in platelets count.

Time frame: Evaluate the treatment of thyroid disorders in improvement in platelets count.

Evaluate if patients have managed according to thyroid disorders, will this affect in their response to ITP management

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Jul 11, 2025
Registry last updated: Jul 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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