Prevalence of Obstructive Sleep Apnea (OSA) and the Association With Cognitive Impairment

The study is aimed to carry out an epidemiology study investigating the prevalence of obstructive sleep apnea (OSA) and the association with cognitive impairment.

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Key information

Conditions

Obstructive Sleep Apnea Apnea Cognition Disorders Cognitive Dysfunction Cognitive Impairment Dyssomnias Mental Disorders Nervous System Diseases Neurocognitive Disorders Respiration Disorders Respiratory Tract Diseases Sleep Apnea Syndromes Sleep Apnea, Obstructive Sleep Disorders, Intrinsic Sleep Wake Disorders

Age range

40 year–74 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Chinese University of Hong

Hong Kong, Please Select

Location status: Recruiting

Location contact

Susanna SS Ng, MBChB

CONTACT

[email protected]

(852) 35053493

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Have stability of at least 4 weeks on permitted medications (i.e. medications known not to affect sleep architecture or circadian rhythms).

Exclusion criteria

Suspected dementia or a score of <24 on the mini-mental state examination
A diagnosis of neurological disorders (e.g. Parkinson's Disease, Epilepsy, Multiple Sclerosis)
Psychiatric disorders including current major depression; bipolar disorder; schizophrenia
Other known clinically significant sleep disorders (e.g. narcolepsy)
Been currently receiving CPAP or bi-level pressure for OSA

Treatment and study plan

Primary outcomes

Number of subjects having apnea-hypopnea index of more than 5

Time frame: 1 year

Secondary outcomes

incidence of cerebrovascular disease

Time frame: 5 years
Montreal Cognitive Assessment

Time frame: 5 years

Sponsors and collaborators

Lead sponsor

Chinese University of Hong Kong

Other

Registry information

Important dates

Study start: 2020
Primary completion: 2026
Study completion: 2026
First posted: Dec 8, 2020
Registry last updated: Feb 20, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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