Prevalence of Lymphoma in IBD

Patients with inflammatory bowel disease (IBD) may be at increased risk of lymphoma. The majority of lymphomas in patients with IBD occur in areas of active inflammation. The relationship between IBD and lymphoproliferative disease is however unclear, since both chronic inflammation as well as medications used to treat IBD (especially immunosuppressives - Azathioprine or 6-MP - and anti-TNF alpha agents) have been associated with increased risk of lymphoma. We plan to study the association between IBD and lymphoma in a large, mixed, community based and referral population from the IBD database at Indiana University.

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Key information

Conditions

Lymphoma Digestive System Diseases Gastroenteritis Gastrointestinal Diseases Hemic and Lymphatic Diseases Immune System Diseases Immunoproliferative Disorders Inflammatory Bowel Disease Inflammatory Bowel Diseases Intestinal Diseases Lymphatic Diseases Lymphoproliferative Disorders Neoplasms Neoplasms by Histologic Type

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Indiana University Medical Center

Indianapolis, Indiana, 46202, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Inflammatory Bowel disease
Lymphoma

Sponsors and collaborators

Lead sponsor

Indiana University

Other

Registry information

Official study title

Prevalence and Risk Factor for Lymphoproliferative Disease in Patients With Inflammatory Bowel Disease

Important dates

Study start: 2006
Primary completion: 2008
Study completion: 2008
First posted: Dec 20, 2007
Registry last updated: Aug 10, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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