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Completed

NCT Number: NCT07033936

Prevalence of Irritable Bowel Syndrome Among Egyptian Medical Students

Assess prevalence of irritable bowel syndrome among both medical students and medical interns, and the most significant risk factors of this condition, and highlight the association between IBS symptoms, anxiety & depression.

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Key information

Age range

18 year–27 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Zagazig University Faculty of Medicine and Affiliated Hospital

Zagazig, Egypt

About this study

One of the most common gastrointestinal disorders is irritable bowel syndrome (IBS). It is a chronic functional bowel disease in which abnormal bowel habits, such as diarrhea, constipation, or both, are associated with abdominal pain and distension. Around 11% of the general population suffers from their symptoms regardless of the geographical distribution.

Irritable bowel syndrome is more common among females and patients younger than 50. For medical students, IBS is common and may affect up to 25% of them.. Especially final-year students, due to the increasing workload of the final year.

Several risk factors increase the prevalence of irritable bowel syndrome, including environmental factors, life events, and junk food abuse. Also, Psychological disorders as severe levels of anxiety, depression, and stress, may contribute to the occurrence of irritable bowel syndrome, and this can be explained by the pathophysiology of IBS, maybe by brain-gut interaction.

Globally, the prevalence of anxiety and depression is higher in medical students compared to other populations, as it reaches up to 38.7% among them. Many factors play a role in increasing the prevalence of anxiety and depression among medical students as stressful courses in medical study, exposure to the death of patients, and others. In Egypt, the prevalence of medical students suffering from stress and anxiety is high due to several problems as financial problems, work overload, traditional methods of education, and the increasing number of students, making communication with thePage 3 of 9 lecturer difficult and that increase incidence of IBS among Egyptian medical students.

Just as anxiety is considered a risk factor for the development of Irritable Bowel Syndrome (IBS), IBS can also lead to the occurrence of anxiety and depression, and that can be explained by brain-gut interaction.

Patients with IBS have a three-times increased risk of either anxiety or depression, compared to healthy subjects.

Although the importance of this topic is recognized, there are limited data about the exact prevalence of irritable bowel syndrome among medical students in Egypt.

Previous studies have discussed this topic in three medical schools in Egypt, but their sample size were too small, and they did not assess the associated anxiety and depression among these students, so no definitive conclusion can be made. This is the first study in Zagazig University hospital to assess the prevalence of irritable bowel syndrome among both medical students and medical interns, and the most significant risk factors of this condition, and highlight the association between IBS symptoms and anxiety and depression.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Egyptian Medical students and interns
  • Their age ranges from 18 to 29 years
  • Have access to online platforms such as Facebook, WhatsApp, and Telegram.
  • Accept to participate in the questionnaire

Exclusion criteria

  • Participate who refused to participate

Treatment and study plan

Questionnaire

Other

An online Questionnaire will be shared via social media such as WhatsApp, Facebook or X for Egyptian medical students and intern to fill

Primary outcomes

  1. Number of irritable bowel syndrome patients among population

    Time frame: 1 month

    Will use Rome IV criteria to diagnose IBS. It is composed of three questions about the presence of GIT symptoms. The presence of at least two of the three diagnoses the IBS.

Secondary outcomes

  1. Number of IBS patients suffering anxiety and depression

    Time frame: 1 month

    Will use the HAD questionnaire to diagnose both anxiety and depression. It is a 14 questionnaire divided into two subscales, one for anxiety and the other for depression. Each question is composed of 4 answers, scored from 0 to 3. Cumulative score for each subscale determines the level of either anxiety or depression. an individual can score between 0 and 21 for either anxiety or depression, and be classified into the following categories: 0 to 7, normal; 8 to 10, borderline; and 11 to 21, abnormal (case)

Sponsors and collaborators

Lead sponsor

Zagazig University

Other Gov

Registry information

Official study title

Prevalence Of Irritable Bowel Syndrome, Its Risk Factors, And Impact On Increasing Anxiety And Depression Among Egyptian Medical Students

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 24, 2025
Registry last updated
Jul 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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