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OpenTrials
Completed

NCT Number: NCT00806000

Prevalence of Exercise-Induced Asthma in Select Cohorts of College Athletes

This study is investigating how commonly exercise-induced asthma happens in athletes and the best way to diagnose exercise-induced asthma. Exercise-induced asthma describes narrowing of the airways in the lungs that occurs in certain people when they exercise. This can cause shortness of breath, cough, and fatigue during exercise and can impair athletic performance. Exercise-induced asthma can be difficult to diagnose. This is a research study, because the investigators are examining the best way to document a diagnosis of exercise-induced asthma. The investigators are also interested in examining why exercise-induced asthma may occur.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

The Ohio State University

Columbus, Ohio, 43210, United States

About this study

prospective, cohort study of the prevalence of asthma in select athletic teams at a large, collegiate athletic program as documented by self-report versus lung function testing. Athletes from men's and women's ice hockey, soccer, and lacrosse will be studied. Each athlete will indicate via self-report on questionnaires whether they have asthma, and then subsequently will be tested utilizing specialized lung function testing. These teams were chosen, because it will allow for gender-matching across teams and they had subjectively reported asthma prevalence rates based on prior pilot data.

Inclusion criteria

  • Varsity athlete on athletic team of interest here at The Ohio State University
  • 18 years of age or older
  • No short-acting bronchodilator use for 6 hours prior to testing
  • No long-acting bronchodilator use for 36 hours prior to testing
  • No inhaled corticosteroids or leukotriene modifiers for 72 hours prior to testing
  • Non-smoker for 6 months or longer
  • Less than 10 pack year (number of packs per day (x) years of smoking=pack years) smoking history, as smoking causes chronic changes in the profile of inflammatory cells of lungs and also makes airways more likely to spasm. This is true even for non-smokers.

Exclusion criteria

  • pregnancy
  • recent upper respiratory tract infection (within 2 weeks of study enrollment)
  • Objective evidence of severe lung impairment on pulmonary testing performed at the beginning of the study.
  • Participation in another interventional research trial
  • Unable to provide consent
  • Asthma exacerbation within the last 4 weeks

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Varsity athlete on athletic team of interest here at The Ohio State University
  • 18 years of age or older
  • No short-acting bronchodilator use for 6 hours prior to testing
  • No long-acting bronchodilator use for 36 hours prior to testing
  • No inhaled corticosteroids or leukotriene modifiers for 72 hours prior to testing
  • Non-smoker for 6 months or longer
  • Less than 10 pack year (number of packs per day (x) years of smoking=pack years) smoking history, as smoking causes chronic changes in the profile of inflammatory cells of lungs and also makes airways more likely to spasm. This is true even for non-smokers

Exclusion criteria

  • pregnancy
  • recent upper respiratory tract infection (within 2 weeks of study enrollment)
  • Objective evidence of severe lung impairment on pulmonary testing performed at the beginning of the study.
  • Participation in another interventional research trial
  • Unable to provide consent
  • Asthma exacerbation within the last 4 weeks

Treatment and study plan

Secondary outcomes

  1. To identify characteristics of athletes that may be associated with increased relative risk for asthma To identify characteristics of athletes that may be associated with increased relative risk for asthma. To identify characteristics of athletes tha

    Time frame: end of study

Sponsors and collaborators

Lead sponsor

Ohio State University

Other

Registry information

Important dates

Study start
2008
Primary completion
2010
Study completion
2010
First posted
Dec 10, 2008
Registry last updated
Oct 10, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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