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NCT Number: NCT06868251

Prevalence and Pattern of Headache in Pediatric Epilepsy

This study aims to determine the prevalence and characteristics of headaches in children with epilepsy, aged 5-18 years. Approximately 60 children will participate at Assiut University Children's Hospital. The research will involve medical history collection, physical and neurological exams, EEG review, and blood tests. The study seeks to improve understanding of the relationship between epilepsy and headaches in children, potentially leading to better treatment strategies. Participation is voluntary, and the risks are minimal.

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Key information

About this study

The primary aim of this observational cross-sectional study is to estimate the prevalence and characterize headaches in pediatric epilepsy patients. Secondary objectives include identifying potential risk factors and triggers associated with headaches in this population and assessing their impact on quality of life.

Participant Criteria

Inclusion criteria

Children aged 5-18 years with epilepsy

Mentally normal and able to describe symptoms

Willing to participate in the study

Exclusion criteria

Children unable to express symptoms due to mental retardation, psychiatric illness, or verbal disability

Children or parents who refuse to participate

Methodology Sample Size: 60 patients, calculated using Epi-info version 7 software, based on a previous study showing 45.7% headache prevalence in pediatric epilepsy patients.

Data Collection:

Detailed medical history, including neurological, cardiovascular, gastrointestinal, endocrine, and musculoskeletal aspects

Comprehensive headache history (onset, location, intensity, quality, duration, frequency, associated symptoms)

Epilepsy history (age of onset, duration, type, medication, seizure control)

General physical examination

Neurological examination

Investigations:

Electroencephalogram (EEG) using Nihon Kohden model 1200

Neuroimaging studies (MRI, CT) if available

Complete Blood Count (CBC)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • pediatric epilepsy patients (5:18 years of age) who are mentally normal and can describe their symptoms.

2/ Acceptance to participate in this study.

Exclusion criteria

  • / Children who can't express their symptoms properly because of mental retardation, psychiatric illness or verbal disability.

2/ Children or Parents who refused to participate in this study.

Treatment and study plan

Primary outcomes

  1. headache prevelance

    Time frame: 1 month

    To estimate the prevalence and characters of headache in pediatric epileptic patients

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Prevalence and Pattern of Comorbid Headache in Pediatric Epilepsy Patients Attending Assiut University Children Hospital.

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Mar 10, 2025
Registry last updated
Mar 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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