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Completed

NCT Number: NCT07563712

Prevalence and Determinant Factors of Postpartum Depression Among Mothers Visiting Postnatal and Immunization Clinics in Selected Public Health Institutions, Mekelle, Tigray

This study looks at depression among mothers after childbirth (also called postpartum depression) in Mekelle City, Tigray, Ethiopia. Postpartum depression is a common mental health condition that can affect women after they give birth. It may cause sadness, loss of interest, fatigue, and difficulty caring for the baby. If not recognized and treated, it can affect both the mother and her child's health and well-being.

The purpose of this study is to find out how common postpartum depression is among mothers visiting public health facilities for postnatal care and child immunization services and to identify factors that may increase the risk. Understanding these factors can help health professionals and policymakers improve support services for mothers.

Mothers who come to selected health facilities for routine postnatal or immunization services will be invited to participate. Participation is voluntary. Those who agree will be asked to complete a questionnaire that includes questions about their mood, social support, economic conditions, and health status. The questionnaire does not include any personal identifiers, so participants' privacy will be protected.

There are no direct medical risks involved in participating in this study. However, some questions may make participants feel emotional when reflecting on their experiences. Participants are free to skip any question or stop at any time. If a mother is found to have symptoms of depression, she will be advised to seek care and may be referred to appropriate health services.

This study may not provide direct benefits to participants, but the findings will help improve understanding of maternal mental health in a post-conflict setting. The results can support the development of better screening, early detection, and support programs for postpartum depression in the community.

Overall, this research aims to contribute to improving the health and well-being of mothers and their children by providing evidence that can guide future healthcare services and policies.

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Key information

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Mekelle general hospital, Yekatit 11 Hospital, Kassech Health Center, Semien Health Center, Adishimdihun Health Center

Mek'ele, Tigray, Ethiopia

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Postnatal women attending postnatal care or vaccination (EPI) services within six weeks of delivery at the selected public health institutions during the study period

Exclusion criteria

  • Women who had a serious illness that prevented participation.
  • Mothers who were unable to attend the selected facilities
  • Mothers who could not communicate effectively,
  • Mothers who had a documented history of severe mental disorders prior to pregnancy (e.g., bipolar disorder or schizophrenia),
  • Mothers who were actively using substances during the data collection period
  • Mothers who had refused to provide informed consent.

Treatment and study plan

Primary outcomes

  1. Postpartum Depression

    Time frame: At the time of interview during the postpartum period (within 6 weeks after delivery)

    Presence of postpartum depression among mothers attending postnatal and immunization services, assessed using a standardized screening tool, the Edinburgh Postnatal Depression Scale (EPDS): scores ≥13 were considered to have postpartum depression

Secondary outcomes

  1. Socio-demographic factors

    Time frame: At the time of interview during the postpartum period (within 6 weeks after delivery)

    Age, marital status, education level, occupation, income, residence, religion

  2. Obstetric and reproductive factors

    Time frame: At the time of interview during the postpartum period (within 6 weeks after delivery)

    Parity, pregnancy intention, mode of delivery, history of complications, number of ANC visits, place of delivery

  3. Psychosocial factors

    Time frame: At the time of interview during the postpartum period (within 6 weeks after delivery)

    Social support, stressful life events, partner support, substance misuse. marriage satisfaction, relation with in-laws

Sponsors and collaborators

Lead sponsor

Mekelle University

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 4, 2026
Registry last updated
May 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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