Prevalence and Clinical Characteristics of Patients With Jackhammer Esophagus and Symptoms of Gastroesophageal Reflux Disease

Gastroesophageal reflux disease (GERD) is involved in the development of esophageal motility disorders like Jackhammer esophagus (JE), a novel hypercontractile condition that was associated with progression to achalasia and limited outcomes following surgical anti-reflux therapy.

This trial was designed to assess the prevalence and characteristics of JE in patients with typical symptoms of GERD and responsiveness to PPI therapy.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Esophageal Motility Disorders Deglutition Disorders Digestive System Diseases Esophageal Diseases Gastrointestinal Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

About this study

Jackhammer esophagus is a novel hypercontractile esophageal disorder. The investigators assess the prevalence and clinical characteristics of patients diagnosed with this disorder out of a collective of patients that are referred with symptoms of gastroesphageal reflux disease and respond to PPI. This is an observational trial.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with symptoms of gastroesophageal reflux disease and diagnosis of Jackhammer esophagus

Exclusion criteria

patients not willing to participate data or undergo screening for gastroesophageal reflux disease

Treatment and study plan

Primary outcomes

Prevalence of Jackhammer esophagus in patients referred with symptoms of gastroesophageal reflux disease

Time frame: January 2014- May 2017

All patients that are referred to our center with symptoms of gastroesophageal reflux disease routinely undergo high-resolution manometry. We assess how many patients are diagnosed with Jackhammer esophagus

Secondary outcomes

Symptom perception

Time frame: January 2014- May 2017

We assess which symptoms are perceived by the patients diagnosed with Jackhammer esophagus. All data are observed during an interview at the high-resolution manometry
Prevalence of gastroesophageal reflux disease in patients with Jackhammer esophagus

Time frame: Januar 2014- May 2017

All patients that are referred to our center are evaluated for gastroesophageal reflux disease. We assess the prevalence of gastroesophageal reflux disease in patients with Jackhammer esophagus diagnosed by ambulatory pH monitoring.

Sponsors and collaborators

Lead sponsor

Medical University of Vienna

Other

Registry information

Important dates

Study start: 2014
Primary completion: 2017
Study completion: 2017
First posted: Nov 20, 2017
Registry last updated: Nov 21, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed