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Completed

NCT Number: NCT04085133

Prevalence and Burden of Bronchiectasis in Tuberculous Patients

Bronchiectasis was described in the early 19th century by Laennec. Bronchiectasis is a chronic condition characterized by permanent and irreversible dilatation of the bronchial airways and impairment of mucociliary transport mechanism due to repeated infection and inflammation leading to colonization of organism and pooling of the mucus in the bronchial tree

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Key information

About this study

Bronchiectasis was described in the early 19th century by Laennec. Bronchiectasis is a chronic condition characterized by permanent and irreversible dilatation of the bronchial airways and impairment of mucociliary transport mechanism due to repeated infection and inflammation leading to colonization of organism and pooling of the mucus in the bronchial tree.

The prevalence of bronchiectasis is age-related and occurs in every age group and in the pre-antibiotic era . it most often began in childhood. Recent evidence shows that bronchiectasis disproportionately affects women and older individuals and will be contributing to increase in healthcare burden.[3] International data show an increase in the prevalence of bronchiectasis over recent years.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1-patients were diagnosed to have tuberculosis by sputum culture and gene x pert.

2-patients were diagnosed to have bronchiectasis after lab and radiological examination as well as clinical score.

3- patients diagnosed as bronchiectasis after history of tuberculosis or anti Tuberculosis treatment with positive or negative tuberculous culture in the time of research.

Exclusion criteria

  • 1-patients presented with other Pulmonary diseases. 2-Chronic liver and renal disease . 3- Lung cancer and tumors. 4- patients were previously diagnosed as bronchiectasis .

Treatment and study plan

Gene Xpert Chest x ray and MSCT chest

Diagnostic Test

Sputum sample for T.B will be done using gene expert device and chest xray and high resolution ct to evaluate bronchectasis

Primary outcomes

  1. To study prevalence of bronchiectasis in TB patients by case per year.

    Time frame: One year

    How many patients of TB will be diagnosed as abronchiectasis

Secondary outcomes

  1. To evaluate the burden of bronchiectasis in TB patients

    Time frame: one year

    by frequency of need for hospital admission per year, need for outpatient clinical visits per month and frequency of need for antimicrobial therapy other than anti-tuberculous treatment per month

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Sep 11, 2019
Registry last updated
Feb 17, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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