Fujian Medical University Union Hospital
Fuzhou, Fujian, 350001, China
NCT Number: NCT04120155
Many thoracic surgeons tend to dissect the inferior pulmonary ligament (IPL) during upper lobectomy, which in theory reduces the free space in the upper thoracic cavity by increasing the mobility of the residual lung. However, the dissection of IPL may lead to bronchial deformation, stenosis, obstruction or lobe torsion, and distortion. Some studies have found that stenosis might be associated with chronic dry cough and shortness of breath, and could result in a significant decline in lung function. Moreover, the dissection of IPL may lead to greater surgical trauma and increase the incidence of complications. Therefore, this study tries to identify whether we should dissect or preserve the inferior pulmonary ligament during the thoracoscopic upper lobectomy.
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Notify Me18 year–70 year
All sexes
Interventional
Not applicable
Fuzhou, Fujian, 350001, China
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Patients will be categorized into two groups: the division group ,who will receive the division of the inferior pulmonary ligament, and the preservation group, who will not.For the dissection group, we will dissect the inferior pulmonary ligament during the surgery.
Patients will be categorized into two groups: the division group ,who will receive the division of the inferior pulmonary ligament, and the preservation group, who will not.For the preservation group, we will preserve the inferior pulmonay ligament during the surgery.
Time frame: 3 months after the operation
Change in bronchial angle of each arm(measured by coronal CT)
Time frame: 6 months after the operation
Change in bronchial angle of each arm(measured by coronal CT)
Time frame: 3 months after the operation
Change in lung volume of each arm(measured by Mimics Research 21.0 software)
Time frame: 6 months after the operation
Change in lung volume of each arm(measured by Mimics Research 21.0 software)
Time frame: Within 6 months after the operation
Apical dead space incidence rate
Time frame: Within 6 months after the operation
Pleural effusion incidence rate
Time frame: Within 6 months after the operation
Lung infection incidence rate
Time frame: During the postoperative hospital stay
Atrial fibrillation incidence rate
Time frame: During the operation
Operation time
Time frame: During the postoperative hospital stay
Postoperative hospital stay
Time frame: During the postoperative hospital stay
Closed thoracic drainage tube rentention time
Time frame: Within one month after the operation
Disposable drainage catheter retention time
Time frame: After the operation
Pathologic cancer stage
Time frame: After the operation
Histologic diagnosis
Fujian Medical University Union Hospital
Other
Preservation vs. Dissection of Inferior Pulmonary Ligament for Thoracoscopic Upper Lobectomy: A Prospective Randomized Controlled Trial(IPLP FJUNION)
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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