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NCT Number: NCT06316154

Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis

The objective of the study is to determine the presence of germinal elements of echinococcosis in the liver parenchyma next to and in the thickness of the fibrous capsule of hydatid cysts.

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Key information

Conditions

Echinococcosis, Hepatic Cestode Infections Digestive System Diseases Echinococcosis Helminthiasis Infections Liver Diseases Liver Diseases, Parasitic Parasitic Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Republican specialized scientific and practical medical center of surgery named after academician V.Vakhidov

Tashkent, Uzbekistan, 100115

Location status: Recruiting

Location contact

Azam Babadjanov, Professor

CONTACT

[email protected]

+998901751703

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Presence of primary or recurrent liver echinococcosis disease requiring surgical treatment
  • Cyst diametr >5 cm;
  • Performing one of the surgical treatment of liver echinococcosis with intraoperative sampling of part of the fibrous capsule with or without adjacent liver tissue for research;
  • Signed informed consent of patients for inclusion in the study;

Exclusion criteria

  • Liver echinococcosis with cysts less than 5 cm in diametr;
  • Presence of severe concomitant disorders

Treatment and study plan

Echinococcectomy

Procedure

Echinococcectomy with subsequent pathomorphological analysis of liver parenchyma next to and in the thickness of the fibrous capsule

Primary outcomes

  1. Presence of viable germinal elements of echinococcosis

    Time frame: 1 day

    Identification of viable germinal elements of echinococcosis according to morphological analysis

Secondary outcomes

  1. Recurrence of liver echinococcosis

    Time frame: 1 year

    Identification of frequency of liver echinococcosis in postoperative period

Sponsors and collaborators

Lead sponsor

Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov

Other

Registry information

Official study title

Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis During Organ-preserving Surgery

Acronym: PAFCLE

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Mar 18, 2024
Registry last updated
Dec 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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