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OpenTrials
Completed

NCT Number: NCT03175640

Prescribe to Save Lives

The U.S. is in the midst of an epidemic of opioid overdose deaths. The common use of opioids among persons living with HIV, along with their common use of benzodiazepines, has resulted in high rates of opioid overdose among this population. This study will test the implementation of evidence-based training, mentoring, technical support, and academic detailing to encourage HIV physicians to adopt evidence-based interventions to reduce overdose risk and treat opioid addiction.

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Key information

Conditions

Opioid-related Disorders Chemically-Induced Disorders Drug Misuse Drug Overdose Mental Disorders Narcotic-Related Disorders Prescription Drug Misuse Substance-Related Disorders

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Massachusetts Medical School - Baystate, Springfield, Massachusetts, United States

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Clinicians and staff of HIV practice sites that:

  • Receive Ryan White Funding;
  • Treat adults with HIV;
  • Have 3 or more prescribing clinicians;
  • Have an electronic medical record (EMR) with an electronic medication list.

Exclusion criteria

  • Sites located in states with fewer than 500 Persons Living With HIV (PLWH) will be excluded

Treatment and study plan

Implementation Intervention

Behavioral

The implementation intervention includes peer-to-peer training, post-training outreach, proactive expert support, and assistance with addressing environmental barriers.

Primary outcomes

  1. Change in naloxone prescribing behavior

    Time frame: baseline to 6 months

    Number of clinicians that prescribe naloxone. This information will be collected from electronic medical record (EMR) data.

Secondary outcomes

  1. Change in perception about pharmacotherapy for opioid use disorder; 6-month

    Time frame: baseline to 6 months

    Opinions About Medication Assisted Treatment (OAMAT) survey

  2. Change in perception about pharmacotherapy for opioid use disorder; 12-month

    Time frame: baseline to 12 months

    Opinions About Medication Assisted Treatment (OAMAT) survey

  3. Change in prescribing motivation; 6 months

    Time frame: baseline to 6 months

    Change in Motivation Scale

  4. Change in prescribing motivation; 12 months

    Time frame: baseline to 12 months

    Change in Motivation Scale

  5. Change in prescriber training

    Time frame: baseline to 12 months

    Number of prescribers that have completed buprenorphine training.

  6. Change in buprenorphine prescribing behavior

    Time frame: baseline to 12 months

    Prevalence of buprenorphine prescription. This information will be collected from EMR data.

Sponsors and collaborators

Lead sponsor

Baystate Medical Center

Other

Collaborators

  • Boston Medical Center
  • National Institute on Drug Abuse (NIDA)
  • Rhode Island Hospital
  • The Miriam Hospital

Registry information

Official study title

Implementation to Motivate Physician Response to Opioid Dependence in HIV Settings

Acronym: PTSL

Important dates

Study start
2017
Primary completion
2019
Study completion
2019
First posted
Jun 5, 2017
Registry last updated
Dec 21, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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