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Completed

NCT Number: NCT00728611

Preparation Rich in Growth Factors (PRGF) Treatment for Osteoarthritis of the Knee

to evaluate the influence of PRGF treatment on patient suffering from OA knee

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Key information

Conditions

Osteoarthritis of the Knee Arthritis Joint Diseases Musculoskeletal Diseases Osteoarthritis Osteoarthritis, Knee Rheumatic Diseases

Age range

40 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Meir Medical Center

Kfar Saba, Israel

About this study

Autologous platelet-secreted growth factors (GFs) may have therapeutic effects in osteoarthritis (OA) capsular joints via multiple mechanisms. Our aim is to examine the effect of a platelet-derived preparation rich in growth factors (PRGFs) in OA knee

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age 40-75 years old
  • diagnosed Oa of the knee more then 1 year
  • no knee deformation

Exclusion criteria

  • mental of physical disabilities
  • pregnancy
  • deformities of the knee

Treatment and study plan

PRGF

Biological

intra auricular injection 6mg

Other names: platelet-derived preparation rich in growth factors

Hyaluronic acid

Drug

20 mg / 2 ml

Other names: Arthrease

Placebo

Drug

physiological water 3cc + lidocain 3cc

Other names: seline 0.9% nacl

Primary outcomes

  1. Improvment of symptomes

    Time frame: 1 year

Sponsors and collaborators

Lead sponsor

Meir Medical Center

Other

Registry information

Official study title

PRP as a Treatment for Knee Osteoarthritis - Randomized-double-blind-placebo Control Trail.

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Aug 6, 2008
Registry last updated
Jul 12, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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