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OpenTrials
Completed

NCT Number: NCT03766646

Preoxygenation With Optiflow™ - the Effect of Speech on Lung Oxygenation.

If a patient speaks during the process of preoxygenation with high-flow nasal oxygen via the Optiflow™ system, is the efficacy reduced as measured by end-tidal lung oxygen content?

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Key information

Conditions

Unrecognized Condition Behavior Communication Speech Verbal Behavior

Age range

18 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

University Hospital Southampton

Southampton, Hants, SO16 6YD, United Kingdom

About this study

This is a randomised controlled trial on 34 patients undergoing routine elective surgery at the Princess Anne Hospital, Southampton. The study will take place from September 2018 to January 2019 and involve preoxygenating all participants for three minutes using the Optiflow™ device. During this time, participants will be instructed to either read aloud a standardised text or to breathe through their nose with a closed mouth. At the end of 3 minutes, the primary outcome, ETO2, will be measured and recorded.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI 18-35, ASA category 1 or 2

Exclusion criteria

  • Inability to read/ follow instructions, Heavily sedated

Treatment and study plan

Optiflow

Device

45l.min oxygen

Other names: HFNO, High Flow Nasal Oxygen

Primary outcomes

  1. End Tidal Oxygen Fraction

    Time frame: At the end of 3 minutes preoxygenation

    Oxygen fraction in first expired breath post preoxygenation

Sponsors and collaborators

Lead sponsor

University Hospital Southampton NHS Foundation Trust

Other

Registry information

Official study title

Preoxygenation With High Flow Nasal Oxygenation Using Optiflow - Does Speech Have an Effect on The End Tidal Oxygen Achieved When Compared to Closed Mouth Nasal Breathing?

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Dec 6, 2018
Registry last updated
Oct 30, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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