Preoperative Inspiratory Muscle Training Effects on the Perioperative Inflammatory Reaction in Cardiac Surgery.

This study evaluates the impact of preoperative high-intensity inspiratory muscle training (IMThi) before cardiac surgery on perioperative inflammatory response. Half participants will receive high intensity inspiratory muscle training and the others a sham inspiratory muscle therapy.

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Key information

Conditions

Thoracic Surgery Inflammation Pathologic Processes Pathological Conditions, Signs and Symptoms Prehabilitation Respiratory Therapy Shock Systemic Inflammatory Response Syndrome

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University Hospital Angers

Angers, 49000, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Waiting for thoracic surgery with valve replacement
Preoperative surgeon consultation between 3 and 6 weeks before surgery

Exclusion criteria

Patient with antecedent of lung surgery
Patient with neuromuscular or neurovascular disease
Non anticipated surgery with a time between surgeon consultation and surgery inferior to 3 weeks.
Inhability to do the preoperative exercises

Treatment and study plan

Prehabilitation with inspiratory muscle training

Other

3 to 6 weeks of two times a day inspiratory muscle training at 80% of the Maximum Inspiratory Pressure.

Primary outcomes

Preoperative STNFr1 level

Time frame: Outcome is evaluated at the training initiation and re evaluated 24hours before the surgery

Post training and preoperative Serum concentration of the SRNFr1 cytokine.

Sponsors and collaborators

Lead sponsor

University Hospital, Angers

Other Gov

Registry information

Official study title

High Intensity Preoperative Inspiratory Muscle Training (IMTHi) Effects on the Perioperative Inflammatory Reaction in Cardiac Surgery With an Associated Biocollection.

Acronym: EMI HiPo

Important dates

Study start: 2018
Primary completion: 2019
Study completion: 2021
First posted: May 18, 2017
Registry last updated: Jan 19, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed