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Completed

NCT Number: NCT03134651

Preoperative Anxiety at Oocyte Retrieval

This study evaluated the effects of preoperative anxiety and dosage of anesthesia on IVF success. Half of participants according to the recorded Beck's Anxiety Inventory (BAI) score: a low-anxiety group, while the other half high-anxiety group.

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Key information

Conditions

Infertility, Female Anesthesia Awareness Anxiety Disorders Anxiety State Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Infertility Intraoperative Awareness Intraoperative Complications Mental Disorders Pathologic Processes Pathological Conditions, Signs and Symptoms Urogenital Diseases

Age range

25 year–43 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

About this study

Anxiety is common among women hospitalized for oocyte retrieval. Infertility is usually accompanied by psychological and behavioral changes and can result in preoperative anxiety. Sometimes, preoperative anxiety can be serious. Furthermore, in the absence of premedication for oocyte retrieval, severe degrees of anxiety may occur. Anxiety effects the total consumption of analgesic and anesthetic drugs intraoperatively and has a negative impact on recovery from anesthesia. In addition, the negative effect of anesthetic agents used on fertilization and embryo quality during in vitro fertilization (IVF) has been discussed. However, the impact of any of them on fertilization and embryo quality has not been clearly determined to date. Studies have reported different results regarding the negative effects of anesthetic agents on embryo development and fertilization.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • oocyte retrieval under sedation
  • 25 and 43 years of age
  • American Society of Anesthesiologists physical status I-II

Exclusion criteria

  • history of psychiatric illness
  • secondary infertility can be surgically corrected
  • not able to communicate well in the native language
  • those women who necessitated general anesthesia

Treatment and study plan

Monitoring brain function

Device

Propofol

Drug

Other names: propofol %1

Primary outcomes

  1. Changes in perioperative Monitoring brain function were measured

    Time frame: Preoperative, intraoperative and postoperative first minute

    Monitoring brain function was assessed Change from baseline at preoperatively, intraoperative 5th and 15th minutes and after anesthesia

Secondary outcomes

  1. pregnancy rate

    Time frame: 10 days

    pregnancy rate

Sponsors and collaborators

Lead sponsor

Trakya University

Other

Registry information

Official study title

The Effect of Preoperative Anxiety With Depth of Anesthesia During Oocyte Retrieval on IVF Success

Important dates

Study start
2014
Primary completion
2016
Study completion
2016
First posted
May 1, 2017
Registry last updated
May 1, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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