Preliminary Research Using Artificial Intelligence Technology to Identify Differences in Facial Expressions Between Healthy People, Patients With Cognitive Decline, and Patients With Dementia

Through artificial intelligence technology, we have conducted a preliminary study aimed at identifying differences in facial expressions among healthy individuals, patients with cognitive decline, and dementia patients. This research offers a novel method and tool for dementia screening, contributing to effective strategies for dementia prevention in our country. By utilizing this approach, we can effectively delay the onset of disability, promote healthy aging among our elderly population, reduce the caregiving burden on individuals, families, and society, and lower medical expenses.

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Key information

Conditions

Artificial Intelligence Technology Behavior Brain Diseases Central Nervous System Diseases Cognition Disorders Cognitive Decline Cognitive Dysfunction Communication Dementia Facial Expression Facial Expressions Identify Mental Disorders Nervous System Diseases Neurocognitive Disorders Nonverbal Communication

Age range

50 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

NTUH

Hsinchu, 300, Taiwan

Location status: Recruiting

Location contact

yang Jung-Cheng

CONTACT

[email protected]

035326151 ext. 523504

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age between 50 and 75 years.

Experimental group:
MCI group: CDR score of 0.5 or MMSE score between 20-25 (mild/early stage).
Dementia group: CDR score greater than 1 or MMSE score between 10-19 (moderate/middle stage).
Control group:
Health group: MMSE score of 26 or above.
Participants must be conscious and able to follow instructions.

Treatment and study plan

Primary outcomes

Facial Expression Test

Time frame: 2024/8/1-2025/10/31

(A) Participants will sit in front of a computer screen and watch videos depicting positive (happy) or negative (sad) emotional stimuli. Each video will be less than 60 seconds long. (B) Participants will undergo the memory recall and calculation ability tests included in the MMSE. (C) While participants are undergoing the tests, video recording equipment will be used to observe and record the facial expression responses of the three groups.

Study contacts

Contact information is provided by the study sponsor or research team.

Yang Jung-Cheng

CONTACT

[email protected]

035326151

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Official study title

Preliminary Study Using Artificial Intelligence Technology to Identify Differences in Facial Expressions Between Healthy People, Patients With Cognitive Decline, and Patients With Dementia

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Jul 22, 2024
Registry last updated: Apr 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed