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NCT Number: NCT07420621

Preliminary Effectiveness of Enhanced Text Message + Incentives

This study is a preliminary evaluation of a smoking cessation intervention designed for pregnant women that combines text message support and financial incentives.

The aims of this study are to determine the preliminary feasibility and acceptability of text message + incentives (intervention) vs. text message only (control).

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Key information

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

University of Kansas Medical Center

Kansas City, Kansas, 66160, United States

Location status: Recruiting

Location contact

Taneisha Scheuermann, PhD

CONTACT

[email protected]

913-588-2641

Taneisha Scheuermann, PhD

PRINCIPAL_INVESTIGATOR

About this study

Pregnant women who smoke and their babies are exposed to known carcinogens and smoking is associated with adverse maternal and birth outcomes. Low-income pregnant women are particularly at risk because they have higher smoking rates and are less likely to quit. Despite continued smoking, most pregnant smokers do not receive smoking cessation counseling and only one in 10 receive referrals to cessation services or follow-up care. Incentives for smoking cessation yield the highest effect sizes of any intervention for pregnant women. Most prior studies evaluating incentives for smoking cessation in this population have used time and resource-intensive in-person visits to verify abstinence for contingent reinforcement. The long-term goal of this research is to reduce the burden of tobacco use by developing and evaluating a highly scalable, effective intervention to support smoking cessation during pregnancy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pregnant women aged: 18+
  • Enrolled in the Special Supplemental Nutrition Program for women, Infants, and Children (WIC) or Medicaid (or applied/applying)
  • Self-reported current daily smokers
  • Able to communicate in English
  • Access to a mobile phone capable of receiving text messages

Exclusion criteria

  • Not at all interested in quitting
  • Smoke less than 24 days in the past month
  • Greater than 30 weeks gestation

Treatment and study plan

Text Messages

Behavioral

Intervention Component - Text messages (SmokeFreeTXT library with pregnancy related messages) participants will receive scheduled messages to support quitting and prevent relapse.

Incentives

Behavioral

Incentives for abstinence - Weeks 1-4; 8; 12: Twice daily CO assessments with verification sent via text-message. Participants will receive daily incentives ranging each day of smoking abstinence.

Primary outcomes

  1. Feasibility of Intervention

    Time frame: 12 weeks post-randomization

    Retention rate.

  2. Smoking Abstinence

    Time frame: 12 weeks post-randomization

    Biochemically verified smoking abstinence (exhaled CO)

  3. Acceptability of Intervention

    Time frame: 12 weeks post-randomization

    Participant ratings of acceptability.

Secondary outcomes

  1. Smoking Abstinence

    Time frame: 26 weeks

    Exhaled CO

Sponsors and collaborators

Lead sponsor

University of Kansas Medical Center

Other

Collaborators

  • National Institute of General Medical Sciences (NIGMS)

Registry information

Official study title

Preliminary Studies on Implementation of Smoking Cessation Interventions for Low-Income Women

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Feb 19, 2026
Registry last updated
Jul 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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