Drugs administration
DrugAntifibrinolytics, analgesics, sedatives, neuromuscular blocking agents
NCT Number: NCT04760977
Up to today, inadequate evidences and knowledge exist about the best prehospital management of hypotensive trauma patients and its clinical consequence on the in-hospital recovery and mortality.
Also new emerging therapies such as prehospital blood transfusion and REBOA (resuscitative endovascular balloon occlusion of the aorta) are lacking strong evidences in, eventually, reducing hospital mortality and improving outcomes.
Moreover, prehospital emergency medicine is throughout Italy an heterogeneous system that has no unique standard operating procedures and, even among HEMS (helicopter emergency medical service), management and therapies on complex trauma patients may vary upon local policies.
With this study we aim to enroll hypotensive trauma patients and study factors of prehospital rescue that can be associated with in-hospital mortality and recovery, eventually even with hospital outcome. For each patients data as demographic, kind of trauma (mechanism, injury scores), therapies and maneuvers will be recorded and then analyzed in comparison with in-hospital data such as need for transfusion, ABG parameters, length of stay (in-ward and ICU), need of therapies like invasive ventilation and renal replacement therapy, recovery and outcome
Interested in participating?
Request Info18 year and older
All sexes
Observational
Ospedale di Alessandria, Alessandria, Italy
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Antifibrinolytics, analgesics, sedatives, neuromuscular blocking agents
Resuscitative technique for exsanguinating traumas
Other names: REBOA
Transfuion of transported blood products for exsanguinating traumas
Stay and play strategy vs scoop and run
Prehospital thorax/abdomen extended focused assessment sonography for trauma
Time frame: 30 days
Time frame: 1 day
Time frame: 6 months
Time frame: 24 hours
Time frame: 24 hours
time from dispatch to hospital admission (if any)
Contact information is provided by the study sponsor or research team.
Lorenzo Gamberini, MD
CONTACT
Marco Tartaglione, MD
CONTACT
Azienda Usl di Bologna
Other Gov
Acronym: SPITFIRE
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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