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Recruiting

NCT Number: NCT05892133

Prehabilitation Effect on Function and Patient Satisfaction Following Total Knee Arthroplasty

Knee arthrosis has a high prevalence. Non-surgical treatment, such as exercise, is the first choice of treatment. However, most patients end up having a surgical procedure such as total knee arthroplasty. Following surgery with total knee replacement as much as 20% of patients report to not be satisfied with the results. It is noteworthy that this level of dissatisfaction has persisted over the last decades despite formidable progress in surgical methods and technology. Leg strength prior to surgery is associated with faster recovery post operatively, which may influence satisfaction. The investigators aim is to implement a period of strength training prior to surgery to evaluate if training prior to surgery may reduce the level of dissatisfaction post operatively.

Recruiting

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Key information

Age range

50 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Molde University College

Molde, Møre og Romsdal, 6410, Norway

Location status: Recruiting

Location contact

Ole Kristian Berg, Dr.

CONTACT

[email protected]

+47 71 19 57 71

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Knee artrosis, refered to surgery

Exclusion criteria

  • Kognitive disability
  • Inflamatory disease in muscles
  • varus/ valgus and extension deficit >15 degrees
  • Neurological disorders

Treatment and study plan

maximal strength training

Behavioral

3 sessions/ week. leg press at ~85% of one repetition maximum for 8 weeks

Primary outcomes

  1. Change in Leg press strength

    Time frame: Baseline, 1 week pre-surgery, 3week post-surgery, 12 months post-surgery.

    The maximal weight that can be lifted once

  2. Group differences in Patient satisfaction

    Time frame: Change from 3 week post-surgery, 12 months post-surgery.

    Satisfied with the results of knee surgery: yes/no

Secondary outcomes

  1. Change in Voluntary activation

    Time frame: Baseline, 1 week pre-surgery, 3week post-surgery.

    Force production of thigh muscle during contraction with superimposed electrical stimulation

  2. Change in Self reported knee function

    Time frame: Baseline, 1 week pre-surgery, 3week post-surgery, 12 months post-surgery.

    The Knee Injury and Osteoarthritis Outcome Score - Physical Function - Short Form

  3. Change in Walking speed

    Time frame: Baseline, 1 week pre-surgery, 3week post-surgery, 12 months post-surgery.

    10 meter walking test

  4. Change in Chair rising ability

    Time frame: Baseline, 1 week pre-surgery, 3week post-surgery, 12 months post-surgery.

    30 second sit to stand test

  5. Change in Balance

    Time frame: Baseline, 1 week pre-surgery, 3week post-surgery, 12 months post-surgery.

    unipedal stance test, postural sway

Study contacts

Contact information is provided by the study sponsor or research team.

Sponsors and collaborators

Lead sponsor

Molde University College

Other

Registry information

Important dates

Study start
2023
Primary completion
2025
Study completion
2030
First posted
Jun 7, 2023
Registry last updated
Dec 15, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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