Prehab Prior to Stem Cell Transplantation in Multiple Myeloma

MOTIVATE is a multi-methods feasibility randomized trial. We will recruit a minimum of 30 individuals with multiple myeloma who are undergoing chemotherapy prior to a Stem Cell Transplant. The study will be conducted in two phases:

Phase I: Feasibility Study The aim of this phase is to determine the feasibility and preliminary effectiveness of a 10-week exercise intervention compared to physical activity counseling alone.

Phase II: Qualitative Study The aim of this phase is to evaluate the acceptability of the Healthy Eating Active Living (HEAL-ME) app design, program delivery/design, and perceived effectiveness of the intervention at the level of the participant.

Inclusion criteria

• Have a diagnosis of Multiple Myeloma
• Be transplant eligible
• Be undergoing chemotherapy prior to, or following an autologous stem cell transplant as part of their cancer treatment; or transplant ineligible.
• Be an Alberta resident
• Be ≥18 years of age
• Be able to read and understand English.

Exclusion criteria

• Their disease status/comorbidities preclude exercise testing or participation
• They are unable to commit to the 10-week exercise program and/or testing sessions at the Cancer Rehabilitation Clinic at the University of Alberta
• They do not have regular access to the internet and/or an electronic device in the home.