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OpenTrials
Completed

NCT Number: NCT00680238

Pregnancy/Implantation Rates Using a Day 3 Score Versus Graduated Embryo Score Plus a Biochemical Marker (sHLA-G)

Objective: To compare pregnancy rates and implantation rates when embryos are selected based on a single Day 3 (D.3) score vs. a GES score plus sHLA-G expression.

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Key information

Conditions

Infertility Abortion, Spontaneous Female Urogenital Diseases and Pregnancy Complications Genital Diseases Pregnancy Complications Urogenital Diseases

Age range

25 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

About this study

Comparing pregnancy rates and implantation rates when embryos are selected using the most common criteria for embryo selection on day 3 - the morphology-(number of blastomere, their shape and size and the percentage of fragmentation)vs a graduated embryo score accumulated over 72 hours and the expression of sHLA-G at 44-46 hours post fertilization.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Self paying ART patients

Exclusion criteria

  • Abnormal uterus
  • Specific Immunologic factors

Treatment and study plan

Human derived FSH

Drug

Customized for each patient

Other names: Bravelle

Primary outcomes

  1. Pregnancy and implantation rates

    Time frame: 12 weeks

Secondary outcomes

  1. Miscarriage rates

    Time frame: 9 months

  2. Miscarriage rates

    Time frame: 9-11 day until βhCG

Sponsors and collaborators

Lead sponsor

University of Stellenbosch

Other

Registry information

Official study title

Pregnancy and Implantation Rates When Embryos Are Selected Based on a Single Day 3 Score (Day 3)vs Graduated Embryo Score(GES) Plus Soluble Human Leukocyte Antigen-G Expression.

Important dates

Study start
2004
Primary completion
2007
Study completion
2007
First posted
May 20, 2008
Registry last updated
May 20, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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