Prefrontal Cortex and Abstract Thinking

The capacity of concept formation is not well understood, even if a link is supposed with the functioning of the frontal lobes.

Our aim is to better understand the cognitive mechanisms underlying this function and to try to correlate the performance with atrophy of the frontal lobe in neurodegenerative diseases involving this region (frontotemporal lobar degeneration and progressive supranuclear palsy).

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Key information

Conditions

Abstract Thinking Concept Formation

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Inserm U 975

Paris, 75013, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

informed consent signed
MMSE> 20
No contra indication to MRI

Exclusion criteria

MMSE<20

Treatment and study plan

Neuropsychological examination

Behavioral

Examination including especially concept formation

MRI

Other

MRI performed in T1-weighted three dimensional sequence

Sponsors and collaborators

Lead sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Other Gov

Registry information

Official study title

Neuropsychological and Anatomical Study of Concept Formation in Frontal Patients

Important dates

Study start: 2010
Study completion: 2011
First posted: Apr 8, 2010
Registry last updated: Dec 9, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.