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Completed

NCT Number: NCT03323671

Preemptive Analgesia for Primary Dysmenorrhoea

Preemptive analgesia before the release of pain mediators

Completed

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Key information

Age range

15 year–25 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Mansoura University

Al Mansurah, 35516, Egypt

About this study

spasmodic dysmenorrhea is one of the most distressing symptoms in women. adolescents shows a usual absence from school . prostaglandin release is one of the most accepted theory responsible for spasmodic dysmenorrhea.

Non steroidal anti inflammatory Drugs were proved to be one of the alternative medications for spasmodic dysmenorrhea.

Getting the idea of what is called preemptive anesthesia by blocking the receptors before catching pain mediators the study participants will be divided randomly into 2 group group 1 receiving ttt 2 days before the anticipated menstruation and group 2 receiving ttt only during menstruation as analgesia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • nulliparous ladies
  • with regular menstrual cycle pattern
  • those experienced history of dysmenorrhea (primary or spasmodic)
  • patients able to sallow tables

Exclusion criteria

  • irregular cycles
  • any associated local causes( pelvic infection, endometriosis, fibroid or others)
  • patients with familial Mediterranean fever or other intermenstrual attacks of abdominal pain
  • gastric or duodenal ulcers or gastritis
  • other contraindications to non steroidal anti-inflammatory drugs
  • patients with severe diminution of vision or color discrimination
  • patients with any depressive or mood disorders
  • patients receiving any hormonal treatment

Treatment and study plan

preemptive mefenamic acid

Drug

preemptive analgesia before menstrual pain

Other names: ponstan forte

mefenamic acid

Drug

mefenamic acid given only during menstruation

Other names: ponstan forte

Primary outcomes

  1. change in the Degree of pain

    Time frame: 4 months

    severity of pain according to visual pain analog scale

Sponsors and collaborators

Lead sponsor

Hanan Nabil

Other

Registry information

Official study title

Preemptive Analgesia for Primary Dysmenorrhoea: a Randomized Controlled Trial

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Oct 27, 2017
Registry last updated
Dec 19, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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