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Completed

NCT Number: NCT00656526

Preemptive Analgesia for Postlaminectomy

To relieve post laminectomy pain, we have tried intraoperative perineural injection of lidocaine right after the exposure in expecting that this would be preemptive analgesia by blocking the nerve transmission so that postoperative pain starts later and lighter.

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Key information

Conditions

Laminectomy Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

harran University Education, Research and application hospital

Sanliurfa, Şanlıurfa, 63000, Turkey (Türkiye)

About this study

A randomized double-blind 40 patients aged 18-50 of ASA I and II undergoing laminectomy were included in the study. All the patients were followed for their heart rate, arterial pressure , respiratory rate, oxygen saturation, end tidal CO2 and postoperative VAS scores.

All the patients were premedicated with midazolam 0.1 mg/kg intramuscularly 40 minutes prior to surgery. The induction was made 2 mg/kg propofol, 1 ug/kg remifentanyl, 0.5mg/kg rocuronium. After the orotracheal intubation anesthesia was maintained with isoflurane (%0.5-2.0) and 0.1 mg/kg rocuronium.Just before the exposure of dorsal root, 0.5 cc %2 lidocaine was injected on the dorsal root.The patients postoperative analgesic period, VAS scores and additional analgesic need was recorded. For the postoperative analgesia tramadol 1 mg/kg tramadol was used.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • laminectomy
  • 18-50 age
  • ASA 1-2
  • both sex

Exclusion criteria

  • under 18 or older than 50
  • any disease other than back pain\\
  • ASA 3-4

Treatment and study plan

Lidocaine, perineural injection, intraoperatively

Drug

0.5 cc lidocaine, one single injection over the dorsal root.

Other names: lidocaine

Lidocaine

Drug

0.5 cc %2 lidocaine,single injection

Primary outcomes

  1. In the laminectomy operation, right after the exposure of the dorsal root , an injection of lidocaine attenuates postoperative pain.

    Time frame: postoperative 24 hours

Sponsors and collaborators

Lead sponsor

Harran University

Other

Registry information

Official study title

Intraoperative Perineural Injection of Lidocaine for Postlaminectomy Pain

Important dates

Study start
2007
Primary completion
2007
Study completion
2007
First posted
Apr 11, 2008
Registry last updated
Apr 11, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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