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Active, Not Recruiting

NCT Number: NCT06373367

Preeclampsia Educational Program Study (PrEPS)

Preeclampsia complicates approximately 8% of all pregnancies. A critical factor of outpatient monitoring is patient education; specifically, education regarding nature of the disease, ongoing short- and long-term risks, and warning signs and symptoms for worsening of disease. This study aims to compare patient knowledge using a novel illustration based app compared to standard discharge instructions.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

MemorialCare Long Beach Medical Center

Long Beach, California, 90806, United States

About this study

Preeclampsia complicates approximately 8% of all pregnancies. While many patients improve following delivery, the disease process remains a leading cause for postpartum morbidity and mortality. A critical factor of outpatient monitoring is patient education; specifically, education regarding nature of the disease, ongoing short- and long-term risks, and warning signs and symptoms for worsening of disease. There is a gap in the literature regarding effective, patient-centered educational tools specifically addressing these elements, especially in the postpartum period.

The investigators propose a pilot, randomized controlled trial of postpartum patients with preeclampsia. The intervention of interest is an illustration-based, educational mobile device application (app) focused on the short- and long-term risks associated with preeclampsia and warning signs and symptoms of worsening disease postpartum. The control for this study will be the same information in a text-only format, also accessed through a mobile device app.

The investigators central hypothesis is that an illustration-based app will improve knowledge of preeclampsia among postpartum patients compared to text-only educational material.

Specific Aim 1: Compare the difference in preeclampsia knowledge score from text-only versus illustration-based education 24 hours post intervention (short-term). The investigators hypothesize that patients who receive illustration-based education will have a) higher preeclampsia knowledge scores at 24 hours post-intervention compared to text-only educational materials and b) a greater increase in preeclampsia knowledge score from baseline (pre-test) compared to text-only education.

Specific Aim 2: Compare the difference in preeclampsia knowledge score from text-only versus illustration-based education >4 weeks post intervention (long-term). The investigators hypothesize that patients who receive illustration-based education will have a) higher preeclampsia knowledge scores at > 4 weeks post-intervention compared to text-only educational materials and b) a greater increase in preeclampsia knowledge score from baseline (pre-test) compared to text-only education.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Preeclampsia with or without severe features
  • Able to read and speak English
  • Consistent access to mobile device with QR-reading capability and ability to access mobile-device application.
  • Pre-and postnatal care provided by OB Clinic (resident clinic) or Magella (maternal-fetal medicine)

Exclusion criteria

  • Patient age < 18 years old
  • Non-English speaking
  • Current enrollment in another trial targeting postpartum preeclampsia parameters
  • Arm width >40cm (XL Cuff)

Treatment and study plan

Illustration based application

Other

Illustrations regarding the cause, risks, and warning signs of preeclampsia

Text based application

Other

Standard preeclampsia discharge instructions

Primary outcomes

  1. Preeclampsia knowledge score - short

    Time frame: Measured at 24 hours postpartum

    Short term preeclampsia knowledge score. Scored from 0-24, with 24 demonstrating the most correct answers to the assessment

Secondary outcomes

  1. Preeclampsia knowledge score - long

    Time frame: Measured between 4 - 6 weeks postpartum

    Long term preeclampsia knowledge score. Scored from 0-24, with 24 demonstrating the most correct answers to the assessment

  2. GAD-7 score

    Time frame: Measured between 4-6 weeks postpartum

    Generalized anxiety score. A score of 0-4 demonstrating none or minimal anxiety, 5-9 mild anxiety, 10-14 moderate anxiety, 15-21 severe anxiety

  3. 72 hour BP check

    Time frame: Measured 72 hours after hospital discharge

    Adherence to a blood pressure check

  4. Number of participants who attend a postpartum visit

    Time frame: Measured within 6 weeks postpartum

    Adherence to one postpartum visit

  5. Daily BP recordings

    Time frame: Measured within 6 weeks postpartum

    Percent of daily blood pressure recordings at home

  6. Accessed material

    Time frame: Measured at 6 weeks postpartum

    Number of times information accessed postpartum

  7. Unplanned readmission

    Time frame: Measured at 6 weeks postpartum

    Number of unplanned readmissions related to preeclampsia

Sponsors and collaborators

Lead sponsor

MemorialCare Health System

Other

Registry information

Official study title

Preeclampsia Educational Program Study

Acronym: PrEPS

Important dates

Study start
2024
Primary completion
2025
Study completion
2026
First posted
Apr 18, 2024
Registry last updated
Oct 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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