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NCT Number: NCT06685224

Prediction of Weaning Outcome From Mechanical Ventilation Using Ultrasound

Examine the predictive value of lung ultrasound in assessing the success of SBTs and tracheal extubation among patients receiving mechanical ventilation in the intensive care unit (ICU).

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Key information

Age range

21 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Mechanically ventilated patients will be included in the study when the underlying disease that had required intubation is considered by the attending physician as reversed and after fulfilling the criteria of weaning (alertness, and Adequate gas exchange, normal pH levels, low and stable doses of vasoactive drugs, normal electrolyte levels, and a rapid shallow breathing index (RSBI) of 105 breaths per minute per liter or lower ) rendering the patient eligible to a first SBT.

Exclusion criteria

  • Exclusion criteria include patients aged < 21yrs , patients with tracheostomy, paraplegia with medullar level above T8, cardiac arrhythmias, severe ICU-acquired neuromyopathy, chronic obstructive pulmonary disease with forced expiratory volume <50% of the theoretical predicted value, patients with planned prophylactic noninvasive ventilation after extubation, and patients who had previously failed a SBT

Treatment and study plan

Ultrasound Assessment of the aeration of lung tissue and Parasternal Intercostal Muscle Thickness

Diagnostic Test

Examine the predictive value of lung ultrasound in assessing the success of SBTs and tracheal extubation among patients receiving mechanical ventilation in the intensive care unit (ICU)

Primary outcomes

  1. The aim of this prospective observational study is to evaluate the predictive value of parasternal intercostal muscle thickness vs ultrasound assessment of lung aeration for prediction of weaning outcome from mechanical ventilation

    Time frame: 6 months

Study contacts

Contact information is provided by the study sponsor or research team.

Mahmoud Tarek Hafez

CONTACT

[email protected]

201221852681

Shaimaa Farouk Abdelkader Mostafa, Professor

CONTACT

[email protected]

201270440771

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

Parasternal Intercostal Muscle Thickness Versus Ultrasound Assessment of Lung Aeration as a Predictor of Weaning From Mechanical Ventilation; a Prospective Observational Study

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Nov 12, 2024
Registry last updated
Jan 27, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.