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OpenTrials
Completed

NCT Number: NCT05788523

Prediction Of Serious Adverse Event in Emergency Department With dysKAlemia, Retrospective Study

Dyskalemia, hypo- and hyperkalemia are common in the emergency department and are associated with increased morbidity and mortality.

The potential seriousness of dyskalemia results from the potential alteration of intracardiac conduction and the increase in cardiac rhythm disorders, all associated with a lethal risk. Given the aspecific symptoms of dyskalemia and the complex causal links to be acquired, it is difficult to judge the severity of the disorders in front of an initial clinical presentation of a patient in the emergency room, as the patient may present a serious condition during his stay in the emergency room, related to the dyskalemia and not prejudged at first. The ECG is recommended to judge the severity of the disorder, in association with the level of kalemia, but the electrical changes of its pattern in the context of dyskalemia are sometimes so fine that even the eye of the practitioner is not able to detect them. To date and to our knowledge, there is no tool for predicting the risk of RTA or death in dyskalemia. The existing studies on the subject, including ECGs, seek to detect dyskalemia and not its complications, and the proposed tools only take into account the ECG and not the clinical context of the patient.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHR Metz-Thionville/Hopital de Mercy

Metz, 57085, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Major patient consulting in an emergency department participating in the study
  • who received at least a digital ECG AND an ionogram in the emergency department during the study period

Exclusion criteria

  • Patient who has expressed opposition to the reuse of their data for the study

Treatment and study plan

Primary outcomes

  1. Number of participants with Cardiac arrest and/or rhythm disorder

    Time frame: within 48 hours

    Number of patients with Cardiac arrest and/or rhythm disorder within 48 hours of the ED visit

Secondary outcomes

  1. Rate of Mortality

    Time frame: within 48 hours

    Rate of Mortality : all causes combined (SAU, hospitalization, SMUR, home)

  2. The type of received treatment for dyskalemia

    Time frame: within 48 hours

    The type of treatment received for dyskalemia (IV and what type, orally and what type)

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Régional Metz-Thionville

Other

Collaborators

  • Georgia Institute of Technology

Registry information

Acronym: PODKA-R

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Mar 29, 2023
Registry last updated
Apr 27, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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