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Completed

NCT Number: NCT07037693

Prediction of Postoperative Outcomes After Rectal Resection by the Comprehensive Complication Index (CCI)

Postoperative complications after rectal resection can worsen the short-term postoperative outcomes and the long-term survival. This study aims to compare the comprehensive complication index (CCI) and the commonly used Clavien-Dindo classification (CDC) in predicting postoperative outcomes after rectal resection.

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Key information

Conditions

Rectal Diseases Digestive System Diseases Gastrointestinal Diseases Intestinal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

HOCH Health Ostschweiz, Kantonsspital St.Gallen

Sankt Gallen, St.Gallen, 9000, Switzerland

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients with rectal resection at the Cantonal Hospital of St.Gallen between 2012 and June 2024.

Exclusion criteria

  • Missing CCI data
  • Missing CDC data
  • Incomplete 30-day follow-up
  • Decline to have their information included in the scientific data analysis
  • Age under 18 years

Treatment and study plan

Comprehensive complication index (CCI)

Diagnostic Test

Comprehensive complication index (CCI)

Clavien-Dindo-Classification (CDC)

Diagnostic Test

Clavien-Dindo-Classification (CDC)

Primary outcomes

  1. Length of hospital stay

    Time frame: Periprocedural

    The predictive ability of the comprehensive-complication index and the Clavien-Dindo classification regarding the length of hospital stay after rectal resection will be compared through an area under the curve (AUC) analysis.

Secondary outcomes

  1. 30-day readmission rate

    Time frame: 30 days

    The predictive ability of the comprehensive-complication index and the Clavien-Dindo classification regarding the 30-day readmission rate after rectal resection will be compared through an area under the curve (AUC) analysis.

  2. 90-day mortality

    Time frame: 90 days

    The predictive ability of the comprehensive-complication index and the Clavien-Dindo classification regarding the 90-day mortality after rectal resection will be compared through an area under the curve (AUC) analysis.

  3. Overall survival

    Time frame: 5 years

    The patients 5-year overall survival will be compared between patients with low comprehensive-complication index and high comprehensive-complication index. A high comprehensive-complication score was defined as a score above the median score of the patients with a Clavien-Dinco classification grad 3a complication.

  4. Comprehensive measure

    Time frame: 30 days

    Evaluation of the comprehensive measure of the comprehensive-complications index through analysis of the number and severity of all complications for patients with multiple complications. Comparison of the range of the comprehensice complications-index score in patients with the same Clavien-Dindo classification.

Sponsors and collaborators

Lead sponsor

Cantonal Hospital of St. Gallen

Other

Registry information

Official study title

Prediction of Postoperative Outcomes After Rectal Resection by the Comprehensive Complication Index (CCI): A Retrospective Comparative Study

Important dates

Study start
2012
Primary completion
2024
Study completion
2024
First posted
Jun 25, 2025
Registry last updated
Jun 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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