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OpenTrials
Completed

NCT Number: NCT02254499

Prediction of Pain After Total Knee Arthroplasty

Despite improvements in treatment, a significant part of patients have severe pain following knee arthroplasty. Preoperative identification of high-risk patients would allow for an intensive individualized analgesic treatment pre- and postoperatively and thus potentially in reduced pain acute and chronically.

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Key information

Conditions

Knee Osteoarthritis Arthritis Joint Diseases Musculoskeletal Diseases Osteoarthritis Osteoarthritis, Knee Rheumatic Diseases

Age range

50 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Gentofte Hospital

Hellerup, 2900, Denmark

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • primary unilateral TKA
  • caucasian
  • 50 - 80 years
  • osteoarthritis

Exclusion criteria

  • deficient written or spoken danish
  • impairment from psychological og neurological disease
  • expected discharged to rehabilitation facility
  • anticoagulant therapy
  • allergies to analgesic treatment
  • hypertension (systolic > 160 / diastolic > 100)
  • ASA class ≥ 4

Treatment and study plan

Primary outcomes

  1. Pain

    Time frame: 24 hours postoperatively

    Pain intensity on a NRS from 0 to 10 upon ambulation 24 hours following surgery

Secondary outcomes

  1. Pain

    Time frame: 48 hours postoperatively

    Pain intensity on a NRS (numeric rank scale) from 0 to 10 upon ambulation 48 hours following surgery

  2. Pain

    Time frame: From day 1 to day 14 following surgery

    Daily diary reported pain intensity on a NRS (numeric rank scale) from 0 to 10 in average and when worse the first two weeks following knee arthroplasty.

Sponsors and collaborators

Lead sponsor

Rigshospitalet, Denmark

Other

Collaborators

  • Lundbeck Foundation

Registry information

Official study title

Prospective Descriptive Study of Nociceptive and Psychological Prediction of Pain After Total Knee Arthroplasty (TKA)

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Oct 2, 2014
Registry last updated
Sep 23, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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