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Completed

NCT Number: NCT03237130

Prediction of Lymphatic Metastasis in Esophageal Cancer by CT Radiomics

This study proposes to establish a CT radiomics-based prediction model for identifying metastasis lymph nodes in esophageal cancer.

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Key information

Conditions

Esophagus Cancer Digestive System Diseases Digestive System Neoplasms Esophageal Diseases Esophageal Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Head and Neck Neoplasms Neoplasms Neoplasms by Site

Sex eligibility

All sexes

Study type

Observational

Primary location

Beijing Cancer Hospital

Beijing, Beijing Municipality, 100142, China

About this study

This study proposes to establish an image feature extraction and selection method for identifying lymph node metastasis of esophageal cancer.The study will consider the relationship between the main lesion and the suspected lymph node, extract association characteristics in order to improve the sensitivity and specificity of the CT radiomics-based prediction model for identifying metastasis lymph nodes. The study includes the construction of CT radiomics-based prediction model and the validation of the prediction model.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • pathologically proven esophageal cancer
  • scheduled to preoperative enhanced chest CT and undergo surgery
  • sign the patient informed consent

Exclusion criteria

  • failed to receive preoperative enhanced chest CT or undergo surgery
  • inavailable pathological results for local lymph node status
  • inquality of CT images for feature extraction
  • patient quit

Treatment and study plan

preoperative enhanced chest CT examination

Procedure

Each patient will receive preoperative enhanced chest CT examination, and their CT images will be used for analysis

Primary outcomes

  1. pathological local lymph node status

    Time frame: Pathologic evaluation will be performed for each patient within 1 week after surgery

    pathological lymph node status is defined as lymph node metastasis exist or not

Sponsors and collaborators

Lead sponsor

Peking University Cancer Hospital & Institute

Other

Registry information

Important dates

Study start
2017
Primary completion
2019
Study completion
2020
First posted
Aug 2, 2017
Registry last updated
Feb 2, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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