Prediction of Hemodynamic Reactivity During Suspension Laryngoscopy Using Analgesia/Nociception Index (ANI)

The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing suspension laryngoscopy on general anesthesia.

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Key information

Conditions

Anesthesia Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hôpital Édouard Herriot, HCL

Lyon, Rhône, 69003, France

About this study

Measurement of analgesia/nociception index at different time points during procedure and assessment of analgesia/nociception index to predict hemodynamic reactivity by building receiver observer's characteristic curve.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age 18-75 years
Suspension laryngoscopy for diagnostic or therapeutic purposes
Total intravenous anesthesia using propofol and remifentanil

Exclusion criteria

age <18 yrs or >75 yrs
arrythmia
administration of anticholinergic drugs or neuromuscular blockade reversal in the 20 previous minutes
psychiatric diseases
autonomic nervous system disorders (epilepsy)

Treatment and study plan

Primary outcomes

Change in heart rate and/or systolic blood pressure by more than 20% within 5 minutes

Time frame: Before induction of anesthesia, 1 min after beginning of procedure, at steady-state anesthesia during procedure (an expected average of 10 min) and at arousal from general anesthesia in the end of procedure (an expected average of 20 min)

Sponsors and collaborators

Lead sponsor

Emmanuel Boselli

Other

Registry information

Official study title

Prediction of Hemodynamic Reactivity During Suspension Laryngoscopy Using Analgesia/Nociception Index (ANI): an Observational Study

Important dates

Study start: 2012
Primary completion: 2013
Study completion: 2013
First posted: Feb 21, 2013
Registry last updated: Jun 10, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed