Intensive care unit, Ambroise Pare Hospital
Boulogne-Billancourt, Hauts-de-seine, 92100, France
NCT Number: NCT03282409
The study aims to develop and validate a prediction score of chronic renal disease occurrence within 3 years after ICU discharge in patients who suffered an acute kidney failure during ICU stay and recovered normal renal function at 90 days following their discharge.
The primary study outcome is the incidence of chronic renal disease within the first 3 years after ICU discharge, defined by a lower glomerular filtration rate (GFR) under 60 mL/minute/1.73m2.
This study is active but is not currently recruiting participants.
Notify Me18 year and older
All sexes
Observational
Boulogne-Billancourt, Hauts-de-seine, 92100, France
As second objectives, the study aims to:
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: At 3 years
Incidence of chronic kidney disease defined by a decreased glomerular filtration rate (GFR) under 60 mL/minute/1.73m2.
Time frame: At 3 years
For patients who have chronic renal disease history and developped an acute kidney failure during ICU stay, progression of chronic renal disease defined by a GFR decline greater than 30% at 3 years.
Time frame: At 3 years
Evolution of urinary protein to creatinine ratio (mg/mmol).
Time frame: At 3 years
For patients who have chronic renal disease history and developped an acute kidney failure during ICU stay, progression of chronic renal disease defined by need to dialysis, or need a renal transplantation, and GFR < 15mL/minute/1.73m2.
Time frame: At 3 years
Cardiovascular events include acute coronary syndrome, ischemic stroke, peripheral artery disease, ventricular rhythm disorder and sudden death.
Thromboembolic events included deep vein thrombosis and pulmonary embolism.
Time frame: At 3 years
All-cause mortality and cardiovascular cause mortality
Time frame: At the end of 1 year
Assessment of quality of life of patients by the scale KDQOL-SF-12. The SF-12 is a short form that includes Items 1-12 as generic core of kidney Disease Quality of Life Instrument (KDQOL).
Time frame: At the end of 1 year
Assessment of quality of life of patients by the scale EQ-5D-5L. The EQ-5D-5L questionnaire consists the descriptive system comprises five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and extreme problems. The patient is asked to indicate his/her health state.
Time frame: At 3 years
Costs related to medical care
Assistance Publique - Hôpitaux de Paris
Other
Acronym: PREDICT
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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