Prediction of Chronic Kidney Disease Following Pre-eclampsia: Diagnosis and Early Care

Pre-eclampsia (PE) is a pregnancy-associated syndrome of variable severity, classically defined by the combination of hypertension and proteinuria in a previously non-hypertensive or proteinuric patient. These symptoms normally resolve within 2-3 months after delivery regardless of the severity of the pre-eclampsia.

Regardless of its definition, preeclampsia is associated with an increased risk of obstetric events and, for the mother, an increased risk of developing chronic kidney disease (CKD), hypertension, diabetes and cardiovascular disease in the broad sense.

The relationship between preeclampsia and Chronic Kidney Disease is, however, complex and not fully understood.

Investigator proposes an interventional study to identify the diagnosis of Chronic Kidney Disease in patients who have developed an episode of Preeclampsia.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Preeclampsia Chronic Disease Disease Attributes Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Hypertension, Pregnancy-Induced Kidney Diseases Male Urogenital Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Pre-Eclampsia Pregnancy Complications Renal Insufficiency Renal Insufficiency, Chronic Urogenital Diseases Urologic Diseases

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Chu Angers, Angers, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Meeting the preeclampsia criteria or one of its complications (eclampsia, HELLP syndrome) according to the ISSHP 2018 definitions within the last 5 years
Having signed the informed consent
Person affiliated to social security

Exclusion criteria

Patient with mental disability or language barrier preventing understanding of the study or consent
Person deprived of liberty by judicial or administrative decision
Person under forced psychiatric care
Person subject to a legal protection measure

Treatment and study plan

annual follow-up during 10 years

Other

an annual follow-up is carried out systematically for a total of 10 years in order to detect the subsequent occurrence of CKD

Primary outcomes

prevalence of the Chronic Kidney Disease (CKD)

Time frame: until 10 years

prevalence of the CKD is measured by the the rate of new CKD Diagnoses (according to the standard definitions)

Study contacts

Contact information is provided by the study sponsor or research team.

Christelle JADEAU

CONTACT

[email protected]

+33 2 44 71 07 81

Sponsors and collaborators

Lead sponsor

Centre Hospitalier le Mans

Other

Registry information

Acronym: PRECEDE

Important dates

Study start: 2022
Primary completion: 2037
Study completion: 2037
First posted: Sep 24, 2021
Registry last updated: Sep 4, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Not Yet Recruiting