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OpenTrials
Completed

NCT Number: NCT06415630

Prediction Models for Postoperative Reintubation in Patients With Acute Aortic Dissection

Reintubation is an adverse postoperative complication in patients with Type A aortic dissection (AAD) that correlates to poor outcomes. This study aims to analyze the risk factors associated with reintubation and to create a fully automated score model to predict the incidence of reintubation. A total of 861 patients diagnosed with AAD and undergoing surgical procedures in a single institution between January 2018 and October 2023 were selected in wuhan Union Hospital. Preoperative and postoperative informmation was used for seeking risk factors and build prediction model for postoperative reintubation. Finally, 5 risk factors wasidentified and a nomogram was established for predicting postoperative reintubation in patients with AAD.

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Key information

Age range

19 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, 430022, China

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

(1) patients diagnosed with AAD admitted for open surgery; (2) aged 18 years or older.

Exclusion criteria

(1) patients deceased during or within 24 hours after surgery; (2) patients with preoperative intubation.

Treatment and study plan

Type A aortic dissection surgery

Procedure

Patients with type A aortic dissection undergone surgery.

Primary outcomes

  1. postoperative reintubation

    Time frame: 3 month

    reintubation incidence in patients with type A aortic dissection undergoing surgery

Sponsors and collaborators

Lead sponsor

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Other

Registry information

Official study title

Multiple Automated Machine-learning Prediction Models for Postoperative Reintubation in Patients With Acute Aortic Dissection

Acronym: ADreintubate

Important dates

Study start
2018
Primary completion
2023
Study completion
2023
First posted
May 16, 2024
Registry last updated
May 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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