Skip to main content
OpenTrials
Completed

NCT Number: NCT06767943

Predicting Myocardial Infarction After Abdominal Surgery: Clinical Scores & Biomarkers

All patients undergoing non-cardiac surgery who met the inclusion criteria underwent a preoperative evaluation using specific assessment tools.

Following surgery, patients were closely monitored in the intermediate care unit for the first 24 hours for the development of acute myocardial infarction (AMI). AMI was diagnosed based on the presence of chest pain, elevated cardiac biomarkers, and specific electrocardiogram (ECG) and echocardiogram findings.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Myocardial Infarction Cardiovascular Diseases Heart Diseases Infarction Ischemia Myocardial Ischemia Necrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Vascular Diseases

Age range

45 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Benha University

Banhā, El Qalyoubia, 13511, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients older than 45,
  • Patients of ASA-PS grade II-IV,
  • Patients who prepared for non-cardiac surgeries of SSS of II-IV,
  • Patients free of exclusion criteria,
  • Patients signed the written consent for the study precipitation.

Exclusion criteria

  • Patients of ASA-PS grade I or V,
  • Patients younger than 60 years,
  • Patients planned to undergo surgeries of SSS >IV,
  • Patients were severely frail with CFS>6,
  • Patients had abnormal preoperative electrocardiography (ECG),
  • Patients had a history of previous major cardiac or cerebrovascular events,
  • Patient had disturbed cognitive function, coagulopathy, severe anemia with hemoglobin concentration (HBC) < 7 gm/dl.

Treatment and study plan

12-lead electrocardiography

Diagnostic Test

All patients were admitted to the intermediate care unit for the 1st 24-h PO for follow-up for the possibility of developing acute myocardial infarction (AMI), which was diagnosed according to the 2017 ESC Guidelines; by 12- lead electrocardiography

Primary outcomes

  1. The proportion of patients reported having at least a 50% incidence of Myocardial Infarction (measured by the Relevant Changes in 12-Leads ECG) in correlation with blood biomarkers.

    Time frame: 50 Days

    The incidence of Myocardial infarction after major abdominal surgery detected by relevant changes in 12 leads ECG and in correlation to presence of blood biomarkers

Sponsors and collaborators

Lead sponsor

Benha University

Other

Registry information

Official study title

Clinical Scoring and Biomarkers for Prediction of Myocardial Infarction After Non-Cardiac Surgery (MINS) Syndrome in Patients Undergoing Major Abdominal Surgeries

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jan 10, 2025
Registry last updated
Apr 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.