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NCT Number: NCT03220373

Predicting Dropout and Outcome From Neuropsychological Functions in SUD Patients

The aim of this project is to gain a more specific understanding of how different cognitive profiles predict residential treatment drop-out, treatment retention and post-treatment outcome in a population with Substance Use Disorder.

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This study is active but is not currently recruiting participants.

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Oslo University Hospital

Oslo, 0320, Norway

About this study

This project collects the neuropsychological profile of residential SUD patients, in addition to treatment length, exit reason, hospital journal data and post-treatment clinical outcome data. The project aims to identify clinically relevant neurocognitive domains that predict treatment dropout and post-treatment clinical outcome. This will make it possible for future clinicians to focus their effort on neurocognitive functions most relevant for this particular patient group.

RESEARCH QUESTIONS:

  • What neurocognitive domain (and sub-domain) are the strongest predictor of treatment drop-out and retention?
  • What neurocognitive domain (and sub-domain) are the strongest predictor of post-treatment clinical outcome variables such as drug use, health and social integration.
  • Will data on treatment length, age, gender, substance abuse history or psychiatric co-morbidity predict outcome independently, or in interaction with, the neuropsychological profile?

This longitudinal prospective cohort study aims for a continuous collection of neuropsychological data baseline and post-treatment follow-up data until 2030.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Substance Use Disorder (SUD) patients.
  • 18 years or older.
  • Qualified to consent to research participation.
  • Able to speak and write in Norwegian.

Exclusion criteria

  • Not qualified to consent to research participation.
  • Insufficient understanding of Norwegian.

Treatment and study plan

Primary outcomes

  1. Exit reason

    Time frame: On average 3 months

    Reason for terminating residential SUD treatment (Treatment completed or Drop-out)

  2. Treatment retention

    Time frame: On average 3 months

    Number of days in treatment

Secondary outcomes

  1. Substance use

    Time frame: 1 year after neuropsychological assessment

    DUDIT (Drug Use Disorders Identification Test)

  2. Psychological distress

    Time frame: 1 year after neuropsychological assessment

    SCL-10 (Symptom Checklist)

  3. Quality of Life

    Time frame: 1 year after neuropsychological assessment

    QoL-5 (Quality of Life)

  4. ADHD symptoms

    Time frame: 1 year after neuropsychological assessment

    ASRS (ADHD Self-Report Scale)

  5. Income

    Time frame: 1 year after neuropsychological assessment

    Nature of income

  6. Housing

    Time frame: 1 year after neuropsychological assessment

    Nature of present accommodation

Sponsors and collaborators

Lead sponsor

Oslo University Hospital

Other

Registry information

Official study title

Predicting Early Treatment Termination (Dropout) and Post-treatment Clinical Outcome From Neuropsychological Functions in Abstinent Substance Use Dependent (SUD) Patients

Important dates

Study start
2017
Primary completion
2029
Study completion
2029
First posted
Jul 18, 2017
Registry last updated
Jan 5, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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