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Completed

NCT Number: NCT06484907

Predicting CSA-AKI With ACTA-PORT Score

In the scope of this study, it will be determined whether the ACTA-PORT (Association of Cardiothoracic Anesthetists perioperative risk of blood transfusion) scoring system can predict the incidence of events in other organ systems, and the feasibility of conducting multiple assessments using a single simple score will be investigated.

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Key information

Conditions

Cardiac Disease Acute Kidney Injury Blood Transfusion Cardiovascular Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Heart Diseases Kidney Diseases Male Urogenital Diseases Renal Insufficiency Urogenital Diseases Urologic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ankara Bilkent City Hospital

Ankara, 06800, Turkey (Türkiye)

About this study

ACTA-PORT (Association of Cardiothoracic Anesthetists perioperative risk of blood transfusion) score is a simple, reliable, and validated tool used to predict the risk of transfusion in patients undergoing heart surgery. In calculating ACTA-PORT score, age, gender, hemoglobin, body surface area, EuroSCORE, creatinine, and type of operation are used.

In this study, it will be determined whether the ACTA-PORT (Association of Cardiothoracic Anesthetists perioperative risk of blood transfusion) scoring system can predict the incidence of events in other organ systems, and the feasibility of conducting multiple assessments using a single simple score will be investigated.

The files of patients undergoing open heart surgery in the cardiovascular surgical operating rooms of Ankara Bilkent City Hospital, along with anesthesia records, transfusion records, and test results identified through the Hospital Information Management System, will be prospectively evaluated. Data will be collected after patients are admitted to the intraoperative and postoperative intensive care unit.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients over 18 years old
  • Patients having open heart surgery
  • Patients undergoing surgery by using cardiopulmonary bypass pump

Exclusion criteria

  • Patients under 18 years old
  • Patients diagnosed with kidney disease

Treatment and study plan

Primary outcomes

  1. KDIGO AKI Staging

    Time frame: Preoperative (last week before operation) and daily after the operation for 7 days

    KDIGO is in the process of developing the Clinical Practice Guideline for Acute Kidney Injury (AKI) and Acute Kidney Disease (AKD). ///// Stage 1: Serum creatinine 1.5-1.9 times baseline or ≥0.3 mg/dl (≥26.5 mmol/l) increase or Urine output <0.5 ml/kg/h for 6-12 hours ////// Stage 2: Serum creatinine 2.0-2.9 times baseline or <0.5 ml/kg/h for ≥12 hours /////// Stage 3: Serum creatinine 3.0 times baseline or Increase in serum creatinine to ≥4.0 mg/dl (≥353.6 mmol/l) or Initiation of renal replacement therapy or in patients <18 years, decrease in eGFR to <35 ml/min per 1.73 m² or Urine output <0.3 ml/kg/h for ≥24 hours or anuria for ≥12 hours

Secondary outcomes

  1. Mechanical Ventilation Duration

    Time frame: the duration after surgery up to a month

    The duration the patient remains intubated from surgery to extubation

  2. Intensive Care Duration

    Time frame: the duration after surgery up to a month

    The duration the patient remains in intensive care unit after surgery

  3. Hospital Stay Duration

    Time frame: the duration after surgery up to a month

    The duration the patient stays in the hospital after surgery until discharge

  4. Mortality

    Time frame: the duration after surgery up to a month

    If the patient dies within 1 month or not

  5. Complications

    Time frame: the duration after surgery up to a month

    Cardiac, Pulmonary, Neurological, Infectious, Thrombotic complications and Presence of MODS (Multiple Organ Dysfunction Syndrome) / SIRS (Systemic Inflammatory Response Syndrome)

  6. Reoperation Necessity

    Time frame: the duration after surgery up to a month

    The need for reoperation due to bleeding

Sponsors and collaborators

Lead sponsor

Ankara City Hospital Bilkent

Other

Registry information

Official study title

Predictive Power of the ACTA-PORT Score for Cardiac Surgery-Associated Acute Kidney Injury: A Prospective Observational Study

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jul 3, 2024
Registry last updated
Jun 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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