Preconditioning Volatile Anesthesia in Liver Surgery

The purpose of this study is to compare the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.

Completed

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Key information

Conditions

Anesthesia

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Universtiy Hospital of Zurich, Department of Visceral and Transplantation Surgery

Zurich, Canton of Zurich, 8091, Switzerland

About this study

Comparing the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

> 18 years
benign and malign disease
any type of liver surgery
inflow occlusion during the liver surgery

Exclusion criteria

< 18 years
participation on other interventional and treatment randomized controlled trials,
trauma of the liver
liver cirrhosis

Treatment and study plan

Primary outcomes

peak ALT and AST levels representing the ischemia-reperfusion injury

Time frame: post-operative

Secondary outcomes

length of hospital stay, length of ICU stay, blood loss and morbidity (post-operative complications)

Time frame: post-operative

Sponsors and collaborators

Lead sponsor

University of Zurich

Other

Registry information

Official study title

Preconditioning is Indeed Protective

Important dates

Study start: 2008
Primary completion: 2009
Study completion: 2009
First posted: Nov 26, 2009
Registry last updated: Nov 26, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed