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NCT Number: NCT05247632

Precision Nutrition and Food Safety for Dietary Prevention of Chronic Disease Study

The associations between food nutrition and safety factors with the risk of chronic diseases are still unclear. This study is conducted in Jinhua, a city with a high prevalence of chronic diseases in China, to assess relations between food nutrition and safety factors and chronic diseases.

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Chronic Diseases Chronic Disease Disease Attributes Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

45 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Lanxi Red Cross Hospital, Lanxi, Zhejiang, China

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About this study

Investigations of associations of food nutrition and safety factors with the risk of chronic diseases are limited and studies in China are still lacking. The investigators aim to collect basic characteristics of participants at baseline, including sex, age, smoking, exercise, marriage, education level, dietary factors, and so on, to assess the association of food nutrition and safety factors including various food items, dietary fatty acids, and internal biomarkers of food contaminants such as acrylamide and 3-MCPD with various chronic diseases in a Chinese middle-aged and elderly population. We will use multi-omics technology to investigate the causal mechanisms. Results from this study will be valuable for chronic diseases prevention in China.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subject aged ≥45 and ≤74 years old
  • Subject has complete data on diet and follow-up time

Exclusion criteria

had the major illness that had made personal life disabled

Treatment and study plan

Primary outcomes

  1. Numbers of participants with metabolic syndrome

    Time frame: From entry into the study baseline:2018 until 2023

    metabolic syndrome

  2. Numbers of participants with obesity

    Time frame: From entry into the study baseline:2018 until 2023

    Obesity

  3. Numbers of participants with diabetes

    Time frame: From entry into the study baseline:2018 until 2023

    Diabetes

Secondary outcomes

  1. Numbers of participants died

    Time frame: From entry into the study baseline:2018 until 2023

    All-cause and cause-specific mortality

  2. Numbers of participants with cardiovascular diseases

    Time frame: From entry into the study baseline:2018 until 2023

    Cardiovascular diseases

Other outcomes

  1. Numbers of participants with fatty liver disease

    Time frame: From entry into the study baseline:2018 until 2023

    Fatty liver disease

Sponsors and collaborators

Lead sponsor

Zhejiang University

Other

Collaborators

  • Lanxi Hospital of Traditional Chinese Medicine
  • Lanxi Red Cross Hospital

Registry information

Official study title

Precision Nutrition and Food Safety for Dietary Prevention of Chronic Disease (PNFS) Study

Acronym: PNFS

Important dates

Study start
2018
Primary completion
2024
Study completion
2028
First posted
Feb 21, 2022
Registry last updated
Jan 10, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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