the Second Xiangya Hospital
Changsha, Hunan, 410010, China
Location status: Recruiting
NCT Number: NCT06320600
The prevalence of diabetes has been increasing year by year. According to the International Diabetes Federation (IDF) statistics in 2021, the global number of people with diabetes has reached 537 million. The patient population is large and heterogeneous, and precise diagnosis and treatment of diabetes patients have been a focus of attention. The objective of this study is to clarify the current status of precision classification and diagnosis of diabetes patients through retrospective and prospective cohort studies, and to establish a model for precision classification and diagnosis of diabetes, improving the accuracy of diabetes classification and diagnosis; based on big data of precision medicine for diabetes patients and follow-up cohorts, to establish precise diagnostic, therapeutic, and predictive methods for diabetes; and through multi-omics data analysis, to explore the potential pathogenesis of diabetes, explaining the heterogeneity of patients, and guiding individualized treatment for patients.
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Observational
Changsha, Hunan, 410010, China
Location status: Recruiting
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
It's an observational study, no intervention included
Time frame: July 1st 2023 to December 31th 2023
To assess the accuracy rate of diabetes classification diagnoses according to "Classification of diabetes mellitus in China: an expert consensus statement" and explore variations across centers in different regions and hospital levels.
Time frame: January 1st 2024 to December 31th 2028
To establish a model for diabetic retinopathy prediction, and calculate the sensitivity and specificity of the model were by comparing with the retinopathy outcome of patients.
Time frame: January 1st 2024 to December 31th 2028
To establish a model for diabetic kidney disease (DKD) prediction, and calculate the sensitivity and specificity of the model were by comparing with the DKD outcome of patients.
Time frame: January 1st 2024 to December 31th 2028
To establish a model for diabetic neuropathy prediction, and calculate the sensitivity and specificity of the model were by comparing with the outcome of patients.
Time frame: January 1st 2024 to December 31th 2028
To establish a model for hypoglycemic therapy selection, and compare the rate of HbA1c<7% in patients who are in accordance with the model choice and those who aren't.
Second Xiangya Hospital of Central South University
Other
Acronym: PDC
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