Precision HD-tACS for Enhancing Sensory Experience in Schizophrenia

Inclusion criteria

for control group and patient:

• Be aged 18 to 65 years inclusive.
• Have read and understood the study information sheet.
• Be affiliated with a social security system or be a beneficiary.
• Have normal or corrected-to-normal vision (glasses or contact lenses).

Exclusion criteria

for control group :

• Any contraindication to tACS, e.g., cardiac pacemaker or other devices that could interfere with the electric field.
• Any contraindication to MRI, e.g., neurological stimulator, pacemaker, cardiac defibrillator, cardiac or vascular prosthesis, intracranial clips or clamps, cerebrospinal fluid shunt, metallic fragments in the eyes, cochlear implants, severe claustrophobia. (A standardized MRI screening questionnaire will be provided.)
• Pregnancy or breastfeeding. (Pregnancy status will be verified with a test on the day of the exam.)
• Legal incapacity (under guardianship, conservatorship, or judicial/administrative detention) or inability to provide informed consent.
• Major psychiatric disorders (excluding tobacco use disorder).
• Neurological disorders.
• Severe somatic disorders that could interfere with participation.
• Uncorrected visual impairments.
• Recent consumption of substances likely to alter brain activity (alcohol, drugs, etc.).
• Presence of any psychiatric disorder.
• Under legal protection (guardianship or conservatorship).

Exclusion criteria

- Patient Group

A potential patient participant will be excluded if they have:

• Any contraindication to tACS, e.g., cardiac pacemaker or other devices that could interfere with the electric field.
• Any contraindication to MRI, e.g., neurological stimulator, pacemaker, cardiac defibrillator, cardiac or vascular prosthesis, intracranial clips or clamps, cerebrospinal fluid shunt, metallic fragments in the eyes, cochlear implants, severe claustrophobia. (A standardized MRI screening questionnaire will be provided.)
• Pregnancy or breastfeeding. (Pregnancy status will be verified with a test on the day of the exam.)
• Legal incapacity (under guardianship, conservatorship, or judicial/administrative detention) or inability to provide informed consent.
• Major psychiatric disorders other than schizophrenia (excluding tobacco use disorder).
• Neurological disorders.
• Severe somatic disorders that could interfere with participation.
• Uncorrected visual impairments.
• Recent consumption of substances likely to alter brain activity (alcohol, drugs, etc.).