University of Miami
Miami, Florida, 33136, United States
NCT Number: NCT05974501
The purpose of this project is to determine if a change in patient reported pain, nausea and vomiting after total knee arthroplasty can be observed with the substitution of a post operative adductor canal block for a preoperative adductor canal block in the current established peri-operative pain protocol and if these changes lead to a decrease in opioid consumption (in morphine equivalents).
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Notify Me18 year and older
All sexes
Interventional
Phase 4
Miami, Florida, 33136, United States
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
1- Patients 18 or older 2 - Patients undergoing primary total knee replacement at the University of Miami Hospital 3 - Patients that have capacity to provide medical consent
Exclusion criteria
Dexamethasone 10mg administered via IV once postoperatively within 24 hours for pain and swelling
1,000mg administered via tablet every 8 hours for pain during the first 1-2 weeks postoperatively
Administered via tablet 75mg nightly for pain during the first 1-2 weeks postoperatively
200mg administered via tablet twice a day for pain and swelling during the first 1-2 weeks postoperatively
30mg administered via IV once postoperatively within 24 hours for pain and swelling
5mg administered via tablet every 4 hours as needed for pain during the first 1-2 weeks postoperatively
20 milliliters Ropivacaine 0.2% administered via injection perioperatively.
Other names: Adductor Canal Block
Time frame: 2 hours postoperatively
Scale with numeric scores ranging from 0 (least) to 10 (most) pain
Time frame: 24 hours postoperatively
Scale with numeric scores ranging from 0 (least) to 10 (most) pain
Time frame: 2 hours postoperatively
Count of the number of patients reporting nausea
Time frame: 2 hours postoperatively
Count of the number of episodes of nausea per patient
Time frame: 24 hours postoperatively
Count of the number of patients reporting nausea
Time frame: 24 hours postoperatively
Count of the number of episodes of nausea per patient
Time frame: 2 hours postoperatively
Count of the number of patients reporting vomiting
Time frame: 2 hours postoperatively
Count of the number of episodes of vomiting per patient
Time frame: 24 hours postoperatively
Count of the number of patients reporting vomiting
Time frame: 24 hours postoperatively
Count of the number of episodes of vomiting per patient
Time frame: 2 hours postoperatively
Measure of the amount of morphine milliequivalents consumed by the patient
Time frame: 24 hours postoperatively
Measure of the amount of morphine milliequivalents consumed by the patient
Time frame: Up to 14 nights postoperatively
Number of nights hospitalized
Time frame: Up to 336 hours postoperatively
Number of hours hospitalized
Time frame: Up to 24 hours postoperatively
The number of patients discharged home by midnight on postoperative day zero
Time frame: Up to 48 hours postoperatively
The number of patients discharged home by midnight postoperative day one
University of Miami
Other
Pre vs. Postoperative Adductor Canal Block for Total Knee Arthroplasty: Prospective Randomized Trial
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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