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OpenTrials
Completed

NCT Number: NCT04769557

Pre Emptive Analgesics for Pain Relief in Impacted Lower Third Molar Surgery

The purpose of the study is to evaluate the efficacy of pre-emptive paracetamol in reducing intra operative pressure and post operative pain after surgical removal of impacted mandibular third molar using visual analogue scale

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Key information

Conditions

Impacted Third Molar Tooth

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Melaka manipal medical college

Malacca, 71510, Malaysia

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 21 years and above
  • Healthy patients (ASA I)
  • Patients who are not allergic to the drugs and local anesthetic agents used

Exclusion criteria

  • Patients who are on concurrent treatment with NSAIDs or corticosteroids
  • Patients with pericoronitis or periapical infection

Treatment and study plan

Paracetamol

Drug

tablet paracetamol 500 mg

Other names: Paracetamol 500 mg

Placebo

Drug

placebo

Primary outcomes

  1. intraoperative pain

    Time frame: during luxation of tooth

    A 10 mm Visual Analogue Scale with higher score depicting severe pain

  2. postoperative pain

    Time frame: 1 day

    A 10 mm Visual analogue scale with higher score depicting severe pain

Secondary outcomes

  1. Time to rescue medication

    Time frame: upto 360 minutes

    minutes

  2. number of patients taking rescue medications

    Time frame: Upto 360 minutes

    Total number of patients taking rescue medications

Sponsors and collaborators

Lead sponsor

Melaka Manipal Medical College

Other

Registry information

Official study title

Pre-emptive Analgesics for Additional Pain Relief in Impacted Third Molar Surgery by depositing4% Articaine With 1:200000 Epinephrine Using Vazirani-Akinosi Closed Mouth Technique- A Randomized Clinical Trial

Important dates

Study start
2017
Primary completion
2019
Study completion
2019
First posted
Feb 24, 2021
Registry last updated
Feb 24, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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