Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07056582

Pre-emptive Analgesia Using Nebulized Ketamine Versus Nebulized Dexmedetomidine in Endoscopic Nasal Surgeries

this study aims to compare the efficacy of pre-emptive nebulized ketamine versus nebulized dexmedetomidine for post operative pain relief in endoscopic nasal surgery

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Nose Diseases Otorhinolaryngologic Diseases Respiratory Tract Diseases

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sohag university hospital

Sohag, Egypt

Location status: Recruiting

Location contact

Magdy M Amin, Professor

CONTACT

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients between the ages of 20 and 60,
  • both sexes,
  • American Society of Anesthesiologists physical status I to II
  • BMI ≥18≤30 kg/m²

Exclusion criteria

  • Patient refusal.
  • patients with advanced respiratory, renal, hepatic, neurological, or psychiatric disease, pregnant or nursing women.
  • patients with a history of allergies to any study drugs.
  • patients who had used central nervous system depressants or analgesics within the previous 24 hours.
  • patients with hypertension, hypotension, or bradycardia.

Treatment and study plan

Dexmedetomidine

Drug

patients in this group will receive nebulized Dexmedetomidine before onset of surgery

ketamine

Drug

patients in this group will receive nebulized ketamine before onset of surgery

0.9%sodium chloride

Drug

patients in this group will receive nebulized 0.9% normal saline before onset of surgery

Primary outcomes

  1. This study aims to assess the efficacy of nebulized dexmedetomidine vs nebulized ketamine to achieve good postoperative pain management in patients undergoing endoscopic nasal surgeries.

    Time frame: 24 hours after operation

    post operative pain management by VAS

Study contacts

Contact information is provided by the study sponsor or research team.

Ahmed T Abdelhameed, Resident

CONTACT

[email protected]

01012833899

Hala M Hashem, Professor

CONTACT

01004385249

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 9, 2025
Registry last updated
Jul 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.