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OpenTrials
Completed

NCT Number: NCT02665897

Pre-eclampsia and Biochemical Markers

In view of both endothelial injury in pre-eclampsia, high blood pressure and kidney impairment characteristics, a recent study demonstrated that the serum levels of NGAL increased at the end of the second trimester in women who subsequently developed pre-eclampsia compared to the control group.

This correlates well with the endothelial damage that occurs during pre-eclampsia and thus NGAL can be considered as a promising marker in predicting both early and late onset pre-eclampsia. It may be required to combine one or more biomarker with NGAL to increase the precision, and sensitivity for detection of risk and reliability of using biomarkers for pre-eclampsia.

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Key information

Conditions

Detection of Preeclampsia Complications

Age range

20 year–40 year

Sex eligibility

Female

Study type

Observational

Primary location

Ahmed Abbas

Assiut, Cairo Governorate, 002, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 20-40 years.
  • Gestational age >20 weeks.

Exclusion criteria

  • Patients with preexisting renal disease,hypertension, diabetes mellitus, gestational hypertension.
  • Patients Refuse to participate in the study
  • Patients already have complicated preeclampsia.

Treatment and study plan

Primary outcomes

  1. The level of circulating NGAL

    Time frame: 24 hours

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Correlation Between Complications of Pre-eclampsia and Detection of Novel Biochemical Markers

Acronym: PET

Important dates

Study start
2016
Primary completion
2016
Study completion
2017
First posted
Jan 28, 2016
Registry last updated
Jun 9, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.